This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Western blot results show a band at 55 kDa, which matches the predicted molecular weight.
This antibody is predicted to detect HDAC2 in Chicken and Bovine samples.
HDAC2 belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HD2; hdac 2; hdac-2; Histone deacetylase 2; Protein deacylase HDAC2; transcriptional regulator homolog RPD3; YY1 transcription factor-binding protein; YY1-associated factor 1
Gene Aliases: D10Wsu179e; HD2; HDAC2; mRPD3; RPD3; YAF1; Yy1bp