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HEMGN regulates the proliferation and differentiation of hematopoietic cells. Overexpression of HEMGN block the TPA-induced megakaryocytic differentiation in the K562 cell model. HEMGN may also prevent cell apoptosis through the activation of the nuclear factor-kappa B (NF-kB).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EDAG-1; Erythroid differentiation-associated gene protein; Hemogen; Hemopoietic gene protein; Negative differentiation regulator protein
Gene Aliases: CT155; EDAG; EDAG-1; HEMGN; NDR; PRO1037; PRO1620
UniProt ID: (Human) Q9BXL5
Entrez Gene ID: (Human) 55363
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