Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
MA5-19463
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2A3
Immunogen
NHLH2 (NP_005590, 36 a.a. ~ 135 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608149
Product Specific Information
Peptide Sequence: SDLEPVEEAE GDGKGGSRAA LYPHPQQLSR EEKRRRRRAT AKYRSAHATR ERIRVEAFN LAFAELRKLL PTLPPDKKLS KIEILRLAIC YISYLNHVLD V
Target Information
The helix-loop-helix (HLH) structures are known motifs commonly found in membrane-active and DNA-binding proteins. Helix-loop-helix proteins (HEN1 and HEN2) are DNA-binding proteins that may be involved in cell-type determination in the early nervous system. Studies of expression in normal tissues have demonstrated expression of NSCL-1 and NSCL-2 (genes encoding HEN1 and HEN2) in the developing central and peripheral nervous system, specifically in developing neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: bHLHa34; bHLHa35; Class A basic helix-loop-helix protein 34; Class A basic helix-loop-helix protein 35; Helix-loop-helix protein 1; Helix-loop-helix protein 2; HEN-1; HEN-2; Nescient helix loop helix 1; Nescient helix loop helix 2; NSCL-1; NSCL-2
Gene Aliases: BHLHA34; BHLHA35; HEN1; HEN2; KIAA0490; NHLH1; NHLH2; NSCL; NSCL1; NSCL2
UniProt ID: (Human) Q02575, (Human) Q02577
Entrez Gene ID: (Human) 4807, (Human) 4808
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein dimerization activity
RNA polymerase II transcription factor activity, sequence-specific DNA binding
RNA polymerase II activating transcription factor binding
protein binding
basic helix-loop-helix transcription factor
transcription from RNA polymerase II promoter
central nervous system development
cell differentiation
positive regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
mating behavior
ovulation cycle
positive regulation of sequence-specific DNA binding transcription factor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support