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This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
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Protein Aliases: FLJ20408; Hairy and enhancer of split 1; Hairy-like; Hairy-like protein; RHL; Transcription factor HES-1
Gene Aliases: bHLHb39; Hes-1; Hes1; Hl; Hry
Molecular Function: basic helix-loop-helix transcription factor