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Product Details
H00028996-M06
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
4E3
Immunogen
HIPK2 (AAG41236.1, 961 a.a. approximately 1065 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).^M
^M
Immunogen sequence: TGNPRTIIVP PLKTQASEVL VECDSLVPVN TSHHSSSYKS KSSSNVTSTS GHSSGSSSGA ITYRQQRPGP HFQQQQPLNL SQAQQHITTD RTGSHRRQQA YITPT
Target Information
HIPK2 is a nuclear serine/threonine kinase that is linked to transcriptional regulation and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: hHIPk2; Homeodomain-interacting protein kinase 2
Gene Aliases: HIPK2; PRO0593
UniProt ID: (Human) Q9H2X6
Entrez Gene ID: (Human) 28996, (Rat) 362342
negative regulation of transcription from RNA polymerase II promoter
positive regulation of protein phosphorylation
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
transforming growth factor beta receptor signaling pathway
smoothened signaling pathway
adult walking behavior
positive regulation of cell proliferation
adult locomotory behavior
anterior/posterior pattern specification
retina layer formation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
neuron differentiation
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of BMP signaling pathway
positive regulation of protein binding
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of DNA binding
negative regulation of neuron apoptotic process
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of JNK cascade
embryonic camera-type eye morphogenesis
voluntary musculoskeletal movement
positive regulation of sequence-specific DNA binding transcription factor activity
embryonic retina morphogenesis in camera-type eye
lens induction in camera-type eye
SMAD protein signal transduction
iris morphogenesis
eye development
transcription, DNA-templated
modulation by virus of host morphology or physiology
erythrocyte differentiation
PML body organization
regulation of cell cycle
cellular response to hypoxia
intrinsic apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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