RP-4917 can be used as a positive control in Western blotting with ABR antibody anti-HIV-1 p24 (PA1-4951, PA1-4952, or PA1-4953), as well as a p24 antigen in detection of anti-HIV-1 p24 antibody in Western blotting or ELISA. Also, it can be used as standard in the titration of p24 antigens as it indicates the AIDS virus amount in virus infection, diagnosis and treatment progress
RP-4917 has a calculated molecular weight of ~24 kDa. Purity is 90%.
HIV-1 Gag p24 is a capsid protein that constitutes the core of the AIDS virus HIV-1 and is produced by the digestion of its precursor Gag p55 by HIV-1 protease. The HIV-1 Gag p24 protein is indispensable to the reproduction of AIDS virus, and constitutes an essential element for the AIDS virus particle construction. HIV-1 Gag p24 is detectable from the early stage of AIDS virus infection, and is used as a marker for observation of the development in the patient's condition after treatment, as it indicated the amount of virus in the blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.