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|Tested species reactivity||Virus|
|Host / Isotype||Rat / IgG1|
|Immunogen||TrpE-Fusion protein produced in X63Ag8.653 cells|
|Contains||0.1% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:1000-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17015 recognizes HIV-2 Nef and does not cross react with HIV-1 Nef.
MA5-17015 has been successfully used in immunoprecipitation and Western blot applications.
The MA5-17015 immunogen is a TrpE-Fusion protein produced in X63Ag8.653 cells.
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects Tcell signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
F-protein; HIV2 nef protein; Human immunodeficiency virus 2 nef; Nefprotein; Negative factor