Product References
Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their immunosuppressive activity.
Nature communications
Piekarska K,Urban-Wójciuk Z,Kurkowiak M,Pelikant-Małecka I,Schumacher A,Sakowska J,Spodnik JH,Arcimowicz Ł,Zielińska H,Tymoniuk B,Renkielska A,Siebert J,Słomińska E,Trzonkowski P,Hupp T,Marek-Trzonkowska NM
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Mon Feb 14 00:00:00 EST 2022
Doxorubicin sensitizes breast cancer cells to natural killer cells in connection with increased Fas receptors.
International journal of molecular medicine
Sawasdee N,Wattanapanitch M,Thongsin N,Phanthaphol N,Chiawpanit C,Thuwajit C,Yenchitsomanus PT,Panya A
11-9983-42 was used in Flow Cytometry, Immunocytochemistry to support the use of combined doxorubicin and NK immunotherapy in BC treatment.
Tue Mar 01 00:00:00 EST 2022
Cancer genes disfavoring T cell immunity identified via integrated systems approach.
Cell reports
Kishton RJ,Patel SJ,Decker AE,Vodnala SK,Cam M,Yamamoto TN,Patel Y,Sukumar M,Yu Z,Ji M,Henning AN,Gurusamy D,Palmer DC,Stefanescu RA,Girvin AT,Lo W,Pasetto A,Malekzadeh P,Deniger DC,Wood KC,Sanjana NE,Restifo NP
11-9983-42 was used in Flow cytometry/Cell sorting to establish that BIRC2 limits antigen presentation and T cell recognition of tumor cells by suppressing IRF1 activity and provide evidence that BIRC2 inhibition in combination with Adoptive T cell therapies is an effective strategy to increase efficacy.
Tue Aug 02 00:00:00 EDT 2022
A Costimulatory CAR Improves TCR-based Cancer Immunotherapy.
Cancer immunology research
Omer B,Cardenas MG,Pfeiffer T,Daum R,Huynh M,Sharma S,Nouraee N,Xie C,Tat C,Perconti S,Van Pelt S,Scherer L,DeRenzo C,Shum T,Gottschalk S,Arber C,Rooney CM
11-9983-42 was used in Flow Cytometry, Immunocytochemistry to demonstrate that the CoCAR can increase the activity of T cells expressing both native and transgenic TCRs and enhance antitumor responses.
Fri Apr 01 00:00:00 EDT 2022
Mesenchymal stem cells negatively regulate CD4+ T cell activation in patients with primary Sjögren syndrome through the miRNA‑125b and miRNA‑155 TCR pathway.
Molecular medicine reports
Gong B,Zheng L,Lu Z,Huang J,Pu J,Pan S,Zhang M,Liu J,Tang J
11-9983 was used in Flow cytometry/Cell sorting to indicate that the expression levels of miRNA‚125b‚5p and miRNA‚155 in TCR‚activated CD4+ T cells from patients with pSS may provide insight regarding autoimmune diseases and offer a novel target for prospective treatment.
Fri Jan 01 00:00:00 EST 2021
Capturing T Lymphocytes' Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy.
Frontiers in immunology
Lemaître F,Carmena Moratalla A,Farzam-Kia N,Carpentier Solorio Y,Tastet O,Cleret-Buhot A,Guimond JV,Haddad E,Arbour N
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Neutralization
Wed Oct 20 00:00:00 EDT 2021
Frequent amplification of HDAC genes and efficacy of HDAC inhibitor chidamide and PD-1 blockade combination in soft tissue sarcoma.
Journal for immunotherapy of cancer
Que Y,Zhang XL,Liu ZX,Zhao JJ,Pan QZ,Wen XZ,Xiao W,Xu BS,Hong DC,Guo TH,Shen LJ,Fan WJ,Chen HY,Weng DS,Xu HR,Zhou PH,Zhang YZ,Niu XH,Zhang X
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Mon Feb 01 00:00:00 EST 2021
Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2.
Molecular therapy. Methods & clinical development
Cabanes-Creus M,Westhaus A,Navarro RG,Baltazar G,Zhu E,Amaya AK,Liao SHY,Scott S,Sallard E,Dilworth KL,Rybicki A,Drouyer M,Hallwirth CV,Bennett A,Santilli G,Thrasher AJ,Agbandje-McKenna M,Alexander IE,Lisowski L
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Fri Jun 12 00:00:00 EDT 2020
TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
International journal of oncology
Uchida E,Suwa S,Yoshimoto R,Watanabe K,Kasama T,Miura O,Fukuda T
11-9983 was used in Flow cytometry/Cell sorting to study the association between chronic myeloid leukemia (CML) and T-lymphokine-activated killer cell-originated protein kinase (TOPK).
Wed May 01 00:00:00 EDT 2019
High-yield isolation of menstrual blood-derived endometrial stem cells by direct red blood cell lysis treatment.
Biology open
Sun Y,Ren Y,Yang F,He Y,Liang S,Guan L,Cheng F,Liu Y,Lin J
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Thu May 02 00:00:00 EDT 2019
High-yield isolation of menstrual blood-derived endometrial stem cells by direct red blood cell lysis treatment.
Biology open
Sun Y,Ren Y,Yang F,He Y,Liang S,Guan L,Cheng F,Liu Y,Lin J
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Thu May 02 00:00:00 EDT 2019
Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment.
Journal of oncology
Li M,Liu Z,Wang X
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Thu Mar 31 00:00:00 EDT 2022
Activated human primary NK cells efficiently kill colorectal cancer cells in 3D spheroid cultures irrespectively of the level of PD-L1 expression.
Oncoimmunology
Lanuza PM,Vigueras A,Olivan S,Prats AC,Costas S,Llamazares G,Sanchez-Martinez D,Ayuso JM,Fernandez L,Ochoa I,Pardo J
11-9983 was used in Flow cytometry/Cell sorting to study the impact of 3D growth on solid cancer immunotherapy.
Tue Jan 12 00:00:00 EST 2021
Role of Nuclear Factor (Erythroid-Derived 2)-Like 2 Signaling for Effects of Fumaric Acid Esters on Dendritic Cells.
Frontiers in immunology
Hammer A,Waschbisch A,Knippertz I,Zinser E,Berg J,Jörg S,Kuhbandner K,David C,Pi J,Bayas A,Lee DH,Haghikia A,Gold R,Steinkasserer A,Linker RA
11-9983 was used in Flow cytometry/Cell sorting to reveal, using treatment with fumaric acid esters as a model, the effects of Nrf2 activation and signalling on dendritic cells.
Wed Nov 20 00:00:00 EST 2019
Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells.
PloS one
Sethumadhavan S,Silva M,Philbrook P,Nguyen T,Hatfield SM,Ohta A,Sitkovsky MV
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Wed Dec 06 00:00:00 EST 2017
Feasibility of placenta-derived mesenchymal stem cells as a tool for studying pregnancy-related disorders.
Scientific reports
Fuchi N,Miura K,Doi H,Li TS,Masuzaki H
11-9983 was used in Flow cytometry/Cell sorting to evaluate the feasibility of using placenta-derived mesenchymal stem cells as a tool to study pregnancy related disorders.
Wed Apr 12 00:00:00 EDT 2017
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.
Cell
Geiger R,Rieckmann JC,Wolf T,Basso C,Feng Y,Fuhrer T,Kogadeeva M,Picotti P,Meissner F,Mann M,Zamboni N,Sallusto F,Lanzavecchia A
11-9983 was used in Flow cytometry/Cell sorting to discover critical changes in the arginine metabolism that lead to a drop in intracellular L-arginine concentration, and characterise the effects in T cells.
Thu Oct 20 00:00:00 EDT 2016
Identification of the Cell-Intrinsic and -Extrinsic Pathways Downstream of EGFR and IFNγ That Induce PD-L1 Expression in Head and Neck Cancer.
Cancer research
Concha-Benavente F,Srivastava RM,Trivedi S,Lei Y,Chandran U,Seethala RR,Freeman GJ,Ferris RL
11-9983 was used in Flow cytometry/Cell sorting to investigate the mechanism by which EGFR and IFNγ upregulate PD-L1 expression in head and neck cancers cells, in the context of JAK/STAT pathway activation, Th1 inflammation, and HPV status.
Tue Mar 01 00:00:00 EST 2016
Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production.
Stem cell research & therapy
Camilleri ET,Gustafson MP,Dudakovic A,Riester SM,Garces CG,Paradise CR,Takai H,Karperien M,Cool S,Sampen HJ,Larson AN,Qu W,Smith J,Dietz AB,van Wijnen AJ
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Thu Aug 11 00:00:00 EDT 2016
Blocking MHC class II on human endothelium mitigates acute rejection.
JCI insight
Abrahimi P,Qin L,Chang WG,Bothwell AL,Tellides G,Saltzman WM,Pober JS
11-9983 was used in Flow cytometry/Cell sorting to establish the immune cell network involved in acute allograft rejection in humans and identify targets for minimising this rejection.
Wed Nov 20 00:00:00 EST 2019
Efficient gene disruption in cultured primary human endothelial cells by CRISPR/Cas9.
Circulation research
Abrahimi P,Chang WG,Kluger MS,Qyang Y,Tellides G,Saltzman WM,Pober JS
11-9983 was used in Flow cytometry/Cell sorting to demonstrate that the CRISPR/Cas9 modification of epithelial cells is a powerful platform for vascular research and for regenerative medicine.
Fri Jul 03 00:00:00 EDT 2015
CD47 is an adverse prognostic factor and a therapeutic target in gastric cancer.
Cancer medicine
Yoshida K,Tsujimoto H,Matsumura K,Kinoshita M,Takahata R,Matsumoto Y,Hiraki S,Ono S,Seki S,Yamamoto J,Hase K
11-9983 was used in Flow cytometry/Cell sorting to demonstrate that higher expressions of CD44 and CD47 in gastric cancer cells correlate with higher proliferation and tumorigenicity.
Tue Sep 01 00:00:00 EDT 2015
Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.
Oncotarget
Yuan D,Xia M,Meng G,Xu C,Song Y,Wei J
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2015
Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.
Oncotarget
Yuan D,Xia M,Meng G,Xu C,Song Y,Wei J
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Tue Oct 06 00:00:00 EDT 2015
Human NK cells activated by EBV+ lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.
Oncoimmunology
Sánchez-Martínez D,Azaceta G,Muntasell A,Aguiló N,Núñez D,Gálvez EM,Naval J,Anel A,Palomera L,Vilches C,Marzo I,Villalba M,Pardo J
11-9983 was used in Flow cytometry/Cell sorting to demonstrate a novel mechanism for natural killer cells to overcome oncogenic alterations that allow haematological cancer cells to evade destruction.
Sun Mar 01 00:00:00 EST 2015
Multifunctional antitumor molecule 5'-triphosphate siRNA combining glutaminase silencing and RIG-I activation.
International journal of cancer
Meng G,Xia M,Xu C,Yuan D,Schnurr M,Wei J
Tue Apr 15 00:00:00 EDT 2014
Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.
Cancer science
Mimura K,Kua LF,Shiraishi K,Kee Siang L,Shabbir A,Komachi M,Suzuki Y,Nakano T,Yong WP,So J,Kono K
11-9983 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which HLA class I and PD-L1 are regulated by MAPK inhibitors and interferon-γ.
Wed Oct 01 00:00:00 EDT 2014
Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling.
Stem cells (Dayton, Ohio)
Fernandez I,Ooi TP,Roy K
Published figure using HLA-ABC monoclonal antibody (Product # 11-9983-42) in Flow Cytometry
Wed Jan 01 00:00:00 EST 2014
IL-22 suppresses IFN-γ-mediated lung inflammation in asthmatic patients.
The Journal of allergy and clinical immunology
Pennino D,Bhavsar PK,Effner R,Avitabile S,Venn P,Quaranta M,Marzaioli V,Cifuentes L,Durham SR,Cavani A,Eyerich K,Chung KF,Schmidt-Weber CB,Eyerich S
11-9983 was used in Flow cytometry/Cell sorting to investigate the anti-inflammatory role for IL-22 in human asthma.
Fri Feb 01 00:00:00 EST 2013
HLA engineering of human pluripotent stem cells.
Molecular therapy : the journal of the American Society of Gene Therapy
Riolobos L,Hirata RK,Turtle CJ,Wang PR,Gornalusse GG,Zavajlevski M,Riddell SR,Russell DW
11-9983 was used in Flow cytometry/Cell sorting to develop two genetic engineering approaches to address the problem of rejection of transplanted cells due to differences in their human leukocyte antigen genes.
Sat Jun 01 00:00:00 EDT 2013
Methylglyoxal modulates immune responses: relevance to diabetes.
Journal of cellular and molecular medicine
Price CL,Hassi HO,English NR,Blakemore AI,Stagg AJ,Knight SC
11-9983 was used in Flow cytometry/Cell sorting to demonstrate that methylglyoxal blocks upregulation of the maturation marker CD83 on dendritic cells, and reduces their ability to stimulate T cells in allogeneic culture.
Tue Jun 01 00:00:00 EDT 2010
Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation.
PLoS genetics
Andrés AM,Dennis MY,Kretzschmar WW,Cannons JL,Lee-Lin SQ,Hurle B,Schwartzberg PL,Williamson SH,Bustamante CD,Nielsen R,Clark AG,Green ED
11-9983 was used in Flow cytometry/Cell sorting to study the haplotypes of ERAP2, a gene with a fundamental role in MHC class I presentation.
Thu Oct 14 00:00:00 EDT 2010
KIR2DS4 is a product of gene conversion with KIR3DL2 that introduced specificity for HLA-A*11 while diminishing avidity for HLA-C.
The Journal of experimental medicine
Graef T,Moesta AK,Norman PJ,Abi-Rached L,Vago L,Older Aguilar AM,Gleimer M,Hammond JA,Guethlein LA,Bushnell DA,Robinson PJ,Parham P
11-9983 was used in Flow cytometry/Cell sorting to reinvestigate the HLA class I specificity of human killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4) and its functional implications.
Mon Oct 26 00:00:00 EDT 2009
Physical and functional interaction of transmembrane thioredoxin-related protein with major histocompatibility complex class I heavy chain: redox-based protein quality control and its potential relevance to immune responses.
Molecular biology of the cell
Matsuo Y,Masutani H,Son A,Kizaka-Kondoh S,Yodoi J
11-9983 was used in Flow cytometry/Cell sorting to suggest a specific role for TMX and its mechanism of action in redox-based ER quality control in relation to MHC class I.
Sun Nov 01 00:00:00 EDT 2009
Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development.
Virology
Li J,Srivastava T,Rawal R,Manuel E,Isbell D,Tsark W,La Rosa C,Wang Z,Li Z,Barry PA,Hagen KD,Longmate J,Diamond DJ
11-9983 was used in Flow cytometry/Cell sorting to develop the Mamu-A01/K(b) Tg mice, which provide a model system to study the Mamu-A01 restricted T-cell response.
Sat Apr 25 00:00:00 EDT 2009
Mamu-A01/K(b) transgenic and MHC Class I knockout mice as a tool for HIV vaccine development.
Virology
Li J,Srivastava T,Rawal R,Manuel E,Isbell D,Tsark W,La Rosa C,Wang Z,Li Z,Barry PA,Hagen KD,Longmate J,Diamond DJ
11-9983 was used in Flow cytometry/Cell sorting to develop the Mamu-A01/K(b) Tg mice, which provide a model system to study the Mamu-A01 restricted T-cell response.
Sat Apr 25 00:00:00 EDT 2009
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I.
Nature immunology
Di Pucchio T,Chatterjee B,Smed-Sörensen A,Clayton S,Palazzo A,Montes M,Xue Y,Mellman I,Banchereau J,Connolly JE
11-9983 was used in Flow cytometry/Cell sorting to demonstrate that pDCs use 'ready made' stores of MHC class I to rapidly present exogenous antigen to CD8+ T cells.
Thu May 01 00:00:00 EDT 2008
Direct proteasome-independent cross-presentation of viral antigen by plasmacytoid dendritic cells on major histocompatibility complex class I.
Nature immunology
Di Pucchio T,Chatterjee B,Smed-Sörensen A,Clayton S,Palazzo A,Montes M,Xue Y,Mellman I,Banchereau J,Connolly JE
11-9983 was used in Flow cytometry/Cell sorting to demonstrate that pDCs use 'ready made' stores of MHC class I to rapidly present exogenous antigen to CD8+ T cells.
Thu May 01 00:00:00 EDT 2008
Polymorphic sites away from the Bw4 epitope that affect interaction of Bw4+ HLA-B with KIR3DL1.
Journal of immunology (Baltimore, Md. : 1950)
Sanjanwala B,Draghi M,Norman PJ,Guethlein LA,Parham P
11-9983 was used in Flow cytometry/Cell sorting to characterise the polymorphic sites throughout the HLA class I molecule that influence the interaction of the Bw4 epitope with KIR3DL1.
Sat Nov 01 00:00:00 EDT 2008
Clinical significance of costimulatory molecules CD80/CD86 expression in IgA nephropathy.
Kidney international
Wu Q,Jinde K,Endoh M,Sakai H
11-9983 was used in Flow cytometry/Cell sorting to suggest that CD80 and CD86 activate T cells in IgAN, CD80/CD86 expressions correlated with renal function at the time of renal biopsy, and monocyte/macrophages and tubular epithelial cells act as APC.
Mon Mar 01 00:00:00 EST 2004
High level of aneuploidy of chromosome 6 by FISH analysis of head and neck squamous cell carcinoma: limited applicability of LOH analysis to define HLA loss.
Human immunology
Koene GJ,Arts-Hilkes YH,van Dijk AJ,van der Ven KJ,Slootweg PJ,de Weger RA,Tilanus MG
Wed Dec 01 00:00:00 EST 2004
A study of human leukocyte antigen G expression in hydatidiform moles.
American journal of obstetrics and gynecology
Goldman-Wohl D,Ariel I,Greenfield C,Hochner-Celnikier D,Lavy Y,Yagel S
Wed Aug 01 00:00:00 EDT 2001