Invitrogen

HLA-ABC Monoclonal Antibody (W6/32), PE, eBioscience™

Product Image Gallery

HLA-ABC Antibody in Flow Cytometry (Flow) — Staining of normal human peripheral blood cells with Mouse IgG2a K Isotype Control PE (Product # 12-4724-81) (blue histogram) or Anti-Human HLA-ABC PE (purple histogram). Cells in the lymphocyte gate were used for analysis.

Product Details

12-9983-42

Applications	Tested Dilution	Publications
Flow Cytometry (Flow)	5 µL (0.25 µg)/test	View 34 publications 34 publications
Immunohistochemistry (Frozen) (IHC (F))	-	View 2 publications 2 publications

Product Specifications
Species Reactivity	Human
Published species	Human, Mouse, Rhesus monkey
Host/Isotype	Mouse / IgG2a, kappa
Recommended Isotype Control	Mouse IgG2a kappa Isotype Control (eBM2a), PE, eBioscience™
Class	Monoclonal
Type	Antibody
Clone	W6/32
Conjugate	PE Alexa Fluor 700 APC Biotin Brilliant UV 395 Brilliant UV 737 FITC Functional Grade NovaFluor Blue 510 NovaFluor Blue 610-70S NovaFluor Blue 660-120S NovaFluor Blue 690 NovaFluor Red 710 NovaFluor Red 725 NovaFluor Red 755 NovaFluor Yellow 590 NovaFluor Yellow 660 NovaFluor Yellow 755 PE-Cyanine5 PE-Cyanine7 PerCP-eFluor 710 Super Bright 436 Super Bright 600 Super Bright 702 Unconjugated
Excitation/Emission Max	565/576 nm View spectra
Form	Liquid
Concentration	5 µL/Test
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.2, with 0.2% BSA
Contains	0.09% sodium azide
Storage conditions	4° C, store in dark, DO NOT FREEZE!
RRID	AB_10547062

Product Specific Information

Description: The W6/32 monoclonal antibody reacts with the human major histocompatibility complex (MHC) class I, HLA-A, B, C. MHC class I antigens associated with beta 2-microglobulin are expressed by all human nucleated cells and are central in cell-mediated immune response and tumor surveillance. W6/32 mAb recognizes a non-polymorphic epitope shared among products of the HLA-A, B, and C loci and immunoprecipitates both 43 kDa and 11-12 kDa chains. Crossreactivity is also seen in baboon, rhesus and cynomolgus monkey.

Applications Reported: The W6/32 antibody has been reported for use in flow cytometric analysis.

Applications Tested: This W6/32 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser.

Filtration: 0.2 µm post-manufacturing filtered.

Target Information

HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Flow Cytometry

Panel Builder

How to use the Panel Builder

Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

Product References

Exploration of the Combination of PLK1 Inhibition with Immunotherapy in Cancer Treatment.

Journal of oncology

Li M,Liu Z,Wang X

12-9983 was used in Flow cytometry/Cell sorting to implicate that the PLK1 inhibition and immunotherapy combination may achieve a synergistic anti-tumour efficacy.

Thu Mar 31 00:00:00 EDT 2022

Novel human liver-tropic AAV variants define transferable domains that markedly enhance the human tropism of AAV7 and AAV8.

Molecular therapy. Methods & clinical development

Cabanes-Creus M,Navarro RG,Zhu E,Baltazar G,Liao SHY,Drouyer M,Amaya AK,Scott S,Nguyen LH,Westhaus A,Hebben M,Wilson LOW,Thrasher AJ,Alexander IE,Lisowski L

12-9983-42 was used in Flow Cytometry to underscore the potential of AAV-SYDs as liver gene therapy vectors and provide insights into the mechanism responsible for their enhanced transduction profile.

Thu Mar 10 00:00:00 EST 2022

Screening HLA-A-restricted T cell epitopes of SARS-CoV-2 and the induction of CD8⁺ T cell responses in HLA-A transgenic mice.

Cellular & molecular immunology

Jin X,Ding Y,Sun S,Wang X,Zhou Z,Liu X,Li M,Chen X,Shen A,Wu Y,Liu B,Zhang J,Li J,Yang Y,Qiu H,Shen C,He Y,Zhao G

12-9983-42 was used in Flow Cytometry to functionally validate T cell epitopes and the development of vaccines that induce specific T cell responses.

Wed Dec 01 00:00:00 EST 2021

Application of counter-selectable marker PIGA in engineering designer deletion cell lines and characterization of CRISPR deletion efficiency.

Nucleic acids research

Li D,Sun X,Yu F,Perle MA,Araten D,Boeke JD

12-9983-42 was used in Flow Cytometry to serve as a general platform with multiple selection markers and may be particularly useful for large scale genome engineering projects such as Genome Project-Write (GP-write).

Thu Mar 18 00:00:00 EDT 2021

hESC-derived immune suppressive dendritic cells induce immune tolerance of parental hESC-derived allografts.

EBioMedicine

Todorova D,Zhang Y,Chen Q,Liu J,He J,Fu X,Xu Y

12-9983 was used in Flow cytometry/Cell sorting to investigate whether the adoptive transfer of CTLA4-Ig/PD-L1 knock-in dendritic cell-like cells(CP DCLs) can induce long-term immune tolerance of parental human embryonic stem cells(hESC)-derived smooth muscle and cardiomyocyte allografts.

Tue Dec 01 00:00:00 EST 2020

Restoring the natural tropism of AAV2 vectors for human liver.

Science translational medicine

Cabanes-Creus M,Hallwirth CV,Westhaus A,Ng BH,Liao SHY,Zhu E,Navarro RG,Baltazar G,Drouyer M,Scott S,Logan GJ,Santilli G,Bennett A,Ginn SL,McCaughan G,Thrasher AJ,Agbandje-McKenna M,Alexander IE,Lisowski L

12-9983-42 was used in Flow Cytometry to derive naturally hepatotropic AAV capsid sequences from primary human liver samples.

Wed Sep 09 00:00:00 EDT 2020

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2.

Molecular therapy. Methods & clinical development

Cabanes-Creus M,Westhaus A,Navarro RG,Baltazar G,Zhu E,Amaya AK,Liao SHY,Scott S,Sallard E,Dilworth KL,Rybicki A,Drouyer M,Hallwirth CV,Bennett A,Santilli G,Thrasher AJ,Agbandje-McKenna M,Alexander IE,Lisowski L

12-9983 was used in Flow cytometry/Cell sorting to investigate if enhanced heparan sulfate proteoglycan binding can negatively affect the in vivo function of otherwise strongly hepatotropic variants and if modulation of the interaction with heparan sulfate proteoglycan is critical to ensure maximum efficiency in vivo.

Fri Jun 12 00:00:00 EDT 2020

Attenuation of Heparan Sulfate Proteoglycan Binding Enhances In Vivo Transduction of Human Primary Hepatocytes with AAV2.

Molecular therapy. Methods & clinical development

Fri Jun 12 00:00:00 EDT 2020

High-Throughput In Vitro, Ex Vivo, and In Vivo Screen of Adeno-Associated Virus Vectors Based on Physical and Functional Transduction.

Human gene therapy

Westhaus A,Cabanes-Creus M,Rybicki A,Baltazar G,Navarro RG,Zhu E,Drouyer M,Knight M,Albu RF,Ng BH,Kalajdzic P,Kwiatek M,Hsu K,Santilli G,Gold W,Kramer B,Gonzalez-Cordero A,Thrasher AJ,Alexander IE,Lisowski L

12-9983 was used in Flow cytometry/Cell sorting to investigate the transduction characteristics of adeno-associated virus vectors using high-throughput screening.

Fri May 01 00:00:00 EDT 2020

Combining DNMT and HDAC6 inhibitors increases anti-tumor immune signaling and decreases tumor burden in ovarian cancer.

Scientific reports

Moufarrij S,Srivastava A,Gomez S,Hadley M,Palmer E,Austin PT,Chisholm S,Diab N,Roche K,Yu A,Li J,Zhu W,Lopez-Acevedo M,Villagra A,Chiappinelli KB

12-9983-42 was used in Flow Cytometry to find that combining DNMTi and HDAC6i results in an amplified type I interferon response, leading to increased cytokine and chemokine expression and higher expression of the MHC I antigen presentation complex in human and mouse ovarian cancer cell lines.

Wed Feb 26 00:00:00 EST 2020

Systematic testing and specificity mapping of alloantigen-specific chimeric antigen receptors in regulatory T cells.

JCI insight

Dawson NA,Lamarche C,Hoeppli RE,Bergqvist P,Fung VC,McIver E,Huang Q,Gillies J,Speck M,Orban PC,Bush JW,Mojibian M,Levings MK

12-9983 was used in Flow cytometry/Cell sorting to characterise and test alloantigen-specific chimeric antigen receptors in regulatory T cells.

Thu Mar 21 00:00:00 EDT 2019

Multiple Knockout of Classical HLA Class II β-Chains by CRISPR/Cas9 Genome Editing Driven by a Single Guide RNA.

Journal of immunology (Baltimore, Md. : 1950)

Crivello P,Ahci M,Maaßen F,Wossidlo N,Arrieta-Bolaños E,Heinold A,Lange V,Falkenburg JHF,Horn PA,Fleischhauer K,Heinrichs S

12-9983 was used in Flow cytometry/Cell sorting to investigate the effects of CRISPR/Cas9 genome editing to simultaneously target HLA-DRB, -DQB1, and -DPB1 through a single guide RNA.

Fri Mar 15 00:00:00 EDT 2019

AG490 reverses phenotypic alteration of dendritic cells by bladder cancer cells.

Oncology letters

Xiu W,Ma J,Lei T,Zhang M

Sat Sep 01 00:00:00 EDT 2018

Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells.

PloS one

Sethumadhavan S,Silva M,Philbrook P,Nguyen T,Hatfield SM,Ohta A,Sitkovsky MV

Published figure using HLA-ABC monoclonal antibody (Product # 12-9983-42) in Flow Cytometry

Wed Dec 06 00:00:00 EST 2017

Frequency and reactivity of antigen-specific T cells were concurrently measured through the combination of artificial antigen-presenting cell, MACS and ELISPOT.

Scientific reports

Shen C,Xu T,Wu Y,Li X,Xia L,Wang W,Shahzad KA,Zhang L,Wan X,Qiu J

12-9983 was used in Flow cytometry/Cell sorting to facilitate the routine analysis of patient-specific cellular immune response pattern to a given antigen in translational studies.

Mon Nov 27 00:00:00 EST 2017

Immune profiling of NF1-associated tumors reveals histologic subtype distinctions and heterogeneity: implications for immunotherapy.

Oncotarget

Haworth KB,Arnold MA,Pierson CR,Choi K,Yeager ND,Ratner N,Roberts RD,Finlay JL,Cripe TP

12-9983 was used in Flow cytometry/Cell sorting to define the immunologic profiles of benign and malignant NF1-related tumours.

Tue Oct 10 00:00:00 EDT 2017

Inhibiting DNA methylation activates cancer testis antigens and expression of the antigen processing and presentation machinery in colon and ovarian cancer cells.

PloS one

Siebenkäs C,Chiappinelli KB,Guzzetta AA,Sharma A,Jeschke J,Vatapalli R,Baylin SB,Ahuja N

12-9983 was used in Flow cytometry/Cell sorting to demonstrate the role of epigenetics in dampening the presentation of cancer testis antigens in colon and ovarian cancer.

Thu Sep 14 00:00:00 EDT 2017

Guanine-Rich Sequences Are a Dominant Feature of Exosomal microRNAs across the Mammalian Species and Cell Types.

PloS one

Momose F,Seo N,Akahori Y,Sawada S,Harada N,Ogura T,Akiyoshi K,Shiku H

12-9983 was used in Flow cytometry/Cell sorting to statistically analyse miRNA microarray data, revealing that guanine-rich sequences are a dominant feature of exosome-dominant miRNAs.

Wed Apr 05 00:00:00 EDT 2017

Identification and validation of multiple cell surface markers of clinical-grade adipose-derived mesenchymal stromal cells as novel release criteria for good manufacturing practice-compliant production.

Stem cell research & therapy

Camilleri ET,Gustafson MP,Dudakovic A,Riester SM,Garces CG,Paradise CR,Takai H,Karperien M,Cool S,Sampen HJ,Larson AN,Qu W,Smith J,Dietz AB,van Wijnen AJ

Published figure using HLA-ABC monoclonal antibody (Product # 12-9983-42) in Flow Cytometry

Thu Aug 11 00:00:00 EDT 2016

Anti-angiogenic efficacy of 5'-triphosphate siRNA combining VEGF silencing and RIG-I activation in NSCLCs.

Oncotarget

Yuan D,Xia M,Meng G,Xu C,Song Y,Wei J

Published figure using HLA-ABC monoclonal antibody (Product # 12-9983-42) in Flow Cytometry

Tue Oct 06 00:00:00 EDT 2015

KIR3DS1-Specific D0 Domain Polymorphisms Disrupt KIR3DL1 Surface Expression and HLA Binding.

Journal of immunology (Baltimore, Md. : 1950)

Mulrooney TJ,Zhang AC,Goldgur Y,Boudreau JE,Hsu KC

12-9983 was used in Flow cytometry/Cell sorting to analyse the functional impact of KIR3DS1-specific polymorphisms on KIR3DL1*009 surface expression, binding to HLA, and functional capacity.

Sat Aug 01 00:00:00 EDT 2015

A truncation variant of the cation channel P2RX5 is upregulated during T cell activation.

PloS one

Abramowski P,Ogrodowczyk C,Martin R,Pongs O

12-9983 was used in Flow cytometry/Cell sorting to show that P2RX5 gene expression of human T lymphocytes is upregulated during activation.

Mon May 18 00:00:00 EDT 2015

Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment.

Cancer science

Mimura K,Kua LF,Shiraishi K,Kee Siang L,Shabbir A,Komachi M,Suzuki Y,Nakano T,Yong WP,So J,Kono K

12-9983 was used in Flow cytometry/Cell sorting to investigate the mechanisms by which HLA class I and PD-L1 are regulated by MAPK inhibitors and interferon-γ.

Wed Oct 01 00:00:00 EDT 2014

Generation of functional, antigen-specific CD8+ human T cells from cord blood stem cells using exogenous Notch and tetramer-TCR signaling.

Stem cells (Dayton, Ohio)

Fernandez I,Ooi TP,Roy K

Published figure using HLA-ABC monoclonal antibody (Product # 12-9983-42) in Flow Cytometry

Wed Jan 01 00:00:00 EST 2014

Alterations of immune response of Non-Small Cell Lung Cancer with Azacytidine.

Oncotarget

Wrangle J,Wang W,Koch A,Easwaran H,Mohammad HP,Vendetti F,Vancriekinge W,Demeyer T,Du Z,Parsana P,Rodgers K,Yen RW,Zahnow CA,Taube JM,Brahmer JR,Tykodi SS,Easton K,Carvajal RD,Jones PA,Laird PW,Weisenberger DJ,Tsai S,Juergens RA,Topalian SL,Rudin CM,Brock MV,Pardoll D,Baylin SB

12-9983 was used in Flow cytometry/Cell sorting to define a biomarker strategy to examine if epigenetic therapy can sensitize patients with non-small cell lung cancer to PD-1 immune checkpoint blockade.

Fri Nov 01 00:00:00 EDT 2013

Age-associated cross-reactive antibody-dependent cellular cytotoxicity toward 2009 pandemic influenza A virus subtype H1N1.

The Journal of infectious diseases

Jegaskanda S,Laurie KL,Amarasena TH,Winnall WR,Kramski M,De Rose R,Barr IG,Brooks AG,Reading PC,Kent SJ

12-9983 was used in cell sorting to assess whether pre-existing antibodies with effector functions provided partial immunity to older individuals during the 2009 influenza A virus H1N1 pandemic.

Tue Oct 01 00:00:00 EDT 2013

HLA-Cw*0102-restricted HIV-1 p24 epitope variants can modulate the binding of the inhibitory KIR2DL2 receptor and primary NK cell function.

PLoS pathogens

Fadda L,Körner C,Kumar S,van Teijlingen NH,Piechocka-Trocha A,Carrington M,Altfeld M

12-9983 was used in Flow cytometry/Cell sorting to demonstrate that sequence variations in position 7 of this epitope observed frequently in naturally occurring HIV-1 sequences can modulate binding to KIR2DL2.

Tue Jan 29 00:00:00 EST 2013

NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.

Nature medicine

Alvarez-Breckenridge CA,Yu J,Price R,Wojton J,Pradarelli J,Mao H,Wei M,Wang Y,He S,Hardcastle J,Fernandez SA,Kaur B,Lawler SE,Vivier E,Mandelboim O,Moretta A,Caligiuri MA,Chiocca EA

12-9983 was used in Flow cytometry/Cell sorting to demonstrate that glioblastoma virotherapy is limited partially by an antiviral NK cell response involving specific NCRs, uncovering new potential targets to enhance cancer virotherapy.

Sat Dec 01 00:00:00 EST 2012

Development of a humanized HLA-A2.1/DP4 transgenic mouse model and the use of this model to map HLA-DP4-restricted epitopes of HBV envelope protein.

PloS one

Ru Z,Xiao W,Pajot A,Kou Z,Sun S,Maillere B,Zhao G,Ojcius DM,Lone YC,Zhou Y

12-9983 was used in Flow cytometry/Cell sorting to develop a model to facilitate the identification of novel HLA-A2- and HLA-DP4-restricted epitopes and vaccine development as well as the characterization of HLA-DP4-restricted responses against infection in humans.

Mon Jul 09 00:00:00 EDT 2012

Chlamydia trachomatis immune evasion via downregulation of MHC class I surface expression involves direct and indirect mechanisms.

Infectious diseases in obstetrics and gynecology

Ibana JA,Schust DJ,Sugimoto J,Nagamatsu T,Greene SJ,Quayle AJ

12-9983 was used in Flow cytometry/Cell sorting to demonstrate that major histocompatibility complex class I downregulation in the presence of Chlamydia trachomatis is mediated by direct and indirect (soluble) factors.

Fri Oct 28 00:00:00 EDT 2011

Cowpox virus inhibits the transporter associated with antigen processing to evade T cell recognition.

Cell host & microbe

Alzhanova D,Edwards DM,Hammarlund E,Scholz IG,Horst D,Wagner MJ,Upton C,Wiertz EJ,Slifka MK,Früh K

12-9983 was used in Flow cytometry/Cell sorting to identify cowpox virus proteins that mediate T cell evasion in multiple hosts.

Thu Nov 19 00:00:00 EST 2009

Cowpox virus inhibits the transporter associated with antigen processing to evade T cell recognition.

Cell host & microbe

Alzhanova D,Edwards DM,Hammarlund E,Scholz IG,Horst D,Wagner MJ,Upton C,Wiertz EJ,Slifka MK,Früh K

12-9983 was used in Flow cytometry/Cell sorting to identify cowpox virus proteins that mediate T cell evasion in multiple hosts.

Thu Nov 19 00:00:00 EST 2009

Construction of soluble Mamu-b*1703, a class I major histocompatibility complex of Chinese rhesus macaques, monomer and tetramer loaded with a simian immunodeficiency virus peptide.

Cellular & molecular immunology

Ouyang D,Wang X,He X,Xu L,Shi H,Gao Q,Guo H

12-9983 was used in an ELISA assay to investigate how some antigenic peptides reported in Indian-origin macaques could be directly recruited as ligands for construction of Chinese macaque MHC tetramers.

Wed Apr 01 00:00:00 EDT 2009

Sensitization of human breast cancer cells to natural killer cell-mediated cytotoxicity by proteasome inhibition.

Clinical and experimental immunology

Ames E,Hallett WH,Murphy WJ

12-9983 was used in Flow cytometry/Cell sorting to investigate whether bortezomib can sensitise human breast cancer cells to killing by the human NK cell line, NK-92.

Sun Mar 01 00:00:00 EST 2009

Signaling of a varicelloviral factor across the endoplasmic reticulum membrane induces destruction of the peptide-loading complex and immune evasion.

The Journal of biological chemistry

Loch S,Klauschies F,Schölz C,Verweij MC,Wiertz EJ,Koch J,Tampé R

12-9983 was used in Flow cytometry/Cell sorting to show that a small viral factor and their signalling across endoplasmic reticulum membranes are essential for targeted degradation of multi-subunit membrane complexes.

Fri May 09 00:00:00 EDT 2008

Identification of a lysosomal peptide transport system induced during dendritic cell development.

The Journal of biological chemistry

Demirel O,Waibler Z,Kalinke U,Grünebach F,Appel S,Brossart P,Hasilik A,Tampé R,Abele R

12-9983 was used in Flow cytometry/Cell sorting to suggest a mechanism by which antigenic peptides have access to the lysosomal compartment in professional antigen-presenting cells.

Fri Dec 28 00:00:00 EST 2007

High level of aneuploidy of chromosome 6 by FISH analysis of head and neck squamous cell carcinoma: limited applicability of LOH analysis to define HLA loss.

Human immunology

Koene GJ,Arts-Hilkes YH,van Dijk AJ,van der Ven KJ,Slootweg PJ,de Weger RA,Tilanus MG

Wed Dec 01 00:00:00 EST 2004

A study of human leukocyte antigen G expression in hydatidiform moles.

American journal of obstetrics and gynecology

Goldman-Wohl D,Ariel I,Greenfield C,Hochner-Celnikier D,Lavy Y,Yagel S

Wed Aug 01 00:00:00 EDT 2001

Bioinformatics

Protein Aliases: A29 protein; alpha chain of MHC class II; antigen presenting molecule; class I MHC, HLA-B antigen; epididymis secretory protein Li 83; H-2K; H-2K(d); H2-K; histocompatibility antigen; HLA -B; HLA A; HLA B-40011; HLA B44; HLA C; HLA class I antigen; HLA class I antigen HLA-B; HLA class I histocompatibility antigen C alpha chain; HLA class I histocompatibility antigen Cw-1 alpha chain; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, A-30 alpha chain; HLA class I histocompatibility antigen, A-33 alpha chain; HLA class I histocompatibility antigen, A-74 alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, B-47 alpha chain; HLA class I histocompatibility antigen, B-50 alpha chain; HLA class I histocompatibility antigen, B-82 alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-15 alpha chain; HLA class I histocompatibility antigen, Cw-18 alpha chain; HLA locus; HLA molecule; HLA-A; HLA-A locus alpha 2 domain; HLA-A null; HLA-Aw33.1; HLA-B; HLA-B 1502; HLA-B alpha chain; HLA-B alpha chain (B*2706); HLA-B alpha chain (B*5002); HLA-B alpha-chain; HLA-B35; HLA-B35 antigen; HLA-Bw50 antigen; HLA-C; HLA-C alpha chain; HLA-C alpha chain (HLA-Cw*15v); HLA-C alpha chain for Cw*18GB; HLA-C alpha-chain; HLA-C antigen; HLA-Cw; HLA-Cw*04GB; HLA-Cw*1702; HLA-Cw*18GB; HLA-Cw-1503; Human leukocyte antigen A; Human leukocyte antigen B; Human leukocyte antigen C; human leukocyte antigen-C alpha chain; hypothetical protein; lecocyte antigen B; leucocyte antigen A; Leukocyte Antigen; leukocyte antigen C; leukocyte antigen class I-A; leukocyte antigen class I-B; Leukoocyte Antigen; lymphocyte antigen; major histocompatability complex B antigen; major histocompatibility antigen HLA-C; MCH class I antigen; MGC184092; MGC7052; MHC 1; MHC antigen; MHC clas I antigen; MHC Class 1; MHC class 1 antigen; MHC class I; MHC class I alpha chain; MHC class I anitgen; MHC class I anti; MHC Class I antigen; MHC class I antigen A*30; MHC class I antigen A*33; MHC class I antigen A*74; MHC class I antigen B*47; MHC class I antigen B*50; MHC class I antigen B*82; MHC class I antigen Cw*15; MHC class I antigen Cw*18; MHC class I antigen GN00104; MHC class I antigen heavy chain; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-A heavy chain; MHC class I antigen HLA-A33; MHC class I antigen HLA-B alpha chain; MHC class I antigen HLA-B heavy chain; MHC class I antigen null protein; MHC class I antigen SHCHA; MHC class I antigene; MHC class I histocompatibility antigen; MHC class I human leukocyte antigen; MHC class I molecule; MHC class I protein; MHC class II antigen; MHC class l antigen; MHC classI antigen; MHC HLA-ABC; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC HLA-B27-HS; MHC HLA-B27d; MHC HLA-B39N; MHC I HLA; MHC1; surface antigen; truncated class I antigen; truncated MHC class I antigen

Gene Aliases: AS; Aw-33; Aw-74; B-4901; B-5001; Bw-47; Bw-50; D6S204; HEL-S-83; HLA-A; HLA-A11; HLA-A33; HLA-B; HLA-B*45ZJ; HLA-B-3506; HLA-B-3905; HLA-B-5502; HLA-B-5602; HLA-B15; HLA-B39; HLA-B49; HLA-B50; HLA-B55; HLA-B59; HLA-B61; HLA-C; HLA-Cw; HLA-DQB1; HLA-DRB1; HLA-JY3; HLAA; HLAB; HLAC; HLC-C; MHC; PSORS1; SPDA1

UniProt ID: (Human) P04439, (Human) P01889, (Human) Q29959

Entrez Gene ID: (Human) 3105, (Human) 3106, (Human) 3107

Molecular Function: major histocompatibility complex protein