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          • Primary Antibodies ›
          • HLA-DR Antibodies
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          Invitrogen

          HLA-DR Monoclonal Antibody (LN3), PE-Cyanine7

          View all (142) HLA-DR antibodies

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          Datasheet
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          Datasheet
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          Cite HLA-DR Monoclonal Antibody (LN3), PE-Cyanine7

          • Antibody Testing Data (1)
          HLA-DR Antibody in Flow Cytometry (Flow)
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          HLA-DR Antibody in Flow Cytometry (Flow)
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          FIGURE: 1 / 1

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          HLA-DR Antibody (A18558) in Flow

          Flow cytometry analysis of HLA-DR using a monoclonal antibody (Product # A18558). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HLA-DR Antibody in Flow Cytometry (Flow)

          Product Details

          A18558

          Applications
          Tested Dilution
          Publications

          Flow Cytometry (Flow)

          Assay-dependent
          -
          Product Specifications

          Host/Isotype

          Mouse / IgG2b, kappa

          Recommended Isotype Control

          Mouse IgG2b kappa Isotype Control (eBMG2b), PE-Cyanine7, eBioscience™

          Class

          Monoclonal

          Type

          Antibody

          Clone

          LN3

          Immunogen

          Synthetic peptide corresponding to the human major histocompatibility complex (MHC) class II, HLA-DR

          Conjugate

          PE-Cyanine7 PE-Cyanine7 PE-Cyanine7
          • Unconjugated
          • Alexa Fluor 660 
          • Alexa Fluor 700 
          • Alexa Fluor Plus 488 
          • Alexa Fluor Plus 647 
          • APC 
          • APC-eFluor 780
          • Biotin 
          • Brilliant UV 395
          • Brilliant UV 496
          • Brilliant UV 563
          • Brilliant UV 615
          • Brilliant UV 661
          • Brilliant UV 737
          • Brilliant UV 805
          • Brilliant Violet 421
          • Brilliant Violet 480
          • Brilliant Violet 605
          • Brilliant Violet 711
          • Brilliant Violet 786
          • eFluor 450
          • eFluor 506
          • FITC
          • NovaFluor Blue 510
          • NovaFluor Blue 530
          • NovaFluor Blue 555
          • NovaFluor Blue 610-30S
          • NovaFluor Blue 660-40S
          • NovaFluor Blue 725
          • NovaFluor Blue 800
          • NovaFluor UV 765
          • NovaFluor Violet 690
          • NovaFluor Violet 800
          • NovaFluor Yellow 810
          • PE 
          • PE-Cyanine5
          • PE-eFluor 610
          • PerCP-Cyanine5.5
          • Super Bright 436
          • Super Bright 600
          • Super Bright 645
          • Super Bright 702
          • Super Bright 780
          • Request custom conjugation

          Excitation/Emission Max

          569/780 nm View spectra spectra

          Form

          Liquid

          Concentration

          3 µg/mL

          Storage conditions

          4°C

          Shipping conditions

          Wet ice

          RRID

          AB_2535392

          Target Information

          HLA-DR, like other MHC class II molecules, is a transmembrane glycoprotein composed of a 36 kDa alpha chain (DRA) and 27 kDa beta chain (DRB). The alpha chain gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. HLA-DR is expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells and activated T lymphocytes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides, present them to T-helper cells, and have a critical role in the initiation of the immune response.

          HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          How to use the Panel Builder

          Watch the video to learn how to use the Invitrogen Flow Cytometry Panel Builder to build your next flow cytometry panel in 5 easy steps.

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