PA5-27338 targets Heme Oxygenase 1 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.
The PA5-27338 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 278 of Human Heme Oxygenase 1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 32-kD; bK286B10; heat shock protein; heat shock protein, 32-kD; heme oxygenase (decycling) 1; Heme oxygenase 1; hemoxygenase; HO-1; P32 protein
Gene Aliases: bK286B10; D8Wsu38e; Hemox; Hmox; HMOX1; HMOX1D; HO; HO-1; HO1; HSP32