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Invitrogen

HNRNPU Polyclonal Antibody

View all (17) hnRNP U antibodies

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HNRNPU Polyclonal Antibody

Product Details

PA5-109827

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:200
-

ELISA (ELISA)

1 µg/mL
-

Immunoprecipitation (IP)

0.5 µg-4 µg antibody for 200 µg-400 µg extracts of
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 608-825 of human hnRNP U (NP_1140322)
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.60 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2855238

Product Specific Information

Immunogen sequence: PKDEDYKQRT QKKAEVEGKD LPEHAVLKMK GNFTLPEVAE CFDEITYVEL QKEEAQKLLE QYKEESKKAL PPEKKQNTGS KKSNKNKSGK NQFNRGGGHR GRGGFNMRGG NFRGGAPGNR GGYNRRGNMP QRGGGGGGSG GIGYPYPRAP VFPGRGSYSN RGNYNRGGMP NRGNYNQNFR GRGNNRGYKN QSQGYNQWQQ GQFWGQKPWS QHYHQGYY

Target Information

The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: contains signal peptide domain; FLJ30202; FLJ37978; GRIP120; Heterogeneous nuclear ribonucleoprotein U; heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); heterogenous nuclear ribonucleoprotein U; hnRNP U; HNRNPU antisense RNA 1; NCRNA00201; nuclear matrix protein sp120; Nuclear p120 ribonucleoprotein; p120; p120 nuclear protein; pp120; SAF-A; SAR-DNA binding protein of the nuclear scaffold; scaffold attachment factor A; Scaffold-attachment factor A; SP120; system N1 Na+ and H+-coupled glutamine transporter; transporter protein; transporter protein; system N1 Na+ and H+-coupled glutamine transporter; U211; unnamed protein product

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Gene Aliases: AA408410; AI256620; AL024194; AL024437; AW557595; C1orf199; C86794; DEE54; EIEE54; GRIP120; hnRNP U; HNRNPU; HNRNPU-AS1; HNRPU; pp120; rCG_20317; SAF-A; SAFA; SN1; Sp120; U21.1

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UniProt ID: (Human) Q00839, (Rat) Q6IMY8, (Mouse) Q8VEK3

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Entrez Gene ID: (Human) 3192, (Rat) 117280, (Mouse) 51810

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Function(s)
nucleotide binding RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II core binding TFIIH-class transcription factor binding DNA binding chromatin binding double-stranded DNA binding single-stranded DNA binding transcription corepressor activity RNA binding double-stranded RNA binding single-stranded RNA binding mRNA 3'-UTR binding actin binding protein binding ATP binding poly(A) binding snRNA binding poly(C) RNA binding chromatin DNA binding poly(G) binding piRNA binding pre-mRNA binding identical protein binding ribonucleoprotein complex binding sequence-specific DNA binding macromolecular complex binding telomerase RNA binding RNA polymerase II C-terminal domain binding lncRNA binding sequence-specific double-stranded DNA binding promoter-specific chromatin binding core promoter binding transporter activity poly(A) RNA binding
Process(es)
osteoblast differentiation transport circadian regulation of gene expression CRD-mediated mRNA stabilization negative regulation of transcription from RNA polymerase II promoter alternative mRNA splicing, via spliceosome regulation of alternative mRNA splicing, via spliceosome mRNA splicing, via spliceosome chromatin organization RNA processing mRNA processing regulation of mitotic cell cycle RNA splicing dosage compensation by inactivation of X chromosome regulation of gene expression positive regulation of macromolecule biosynthetic process mRNA metabolic process cell differentiation erythrocyte differentiation chromatin silencing by small RNA negative regulation of telomere maintenance via telomerase negative regulation of kinase activity negative regulation of transcription elongation from RNA polymerase II promoter positive regulation of transcription from RNA polymerase II promoter mRNA stabilization rhythmic process cell division maintenance of protein location in nucleus cardiac muscle cell development random inactivation of X chromosome cellular response to glucocorticoid stimulus positive regulation of brown fat cell differentiation dendritic transport of messenger ribonucleoprotein complex negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay regulation of mitotic spindle assembly regulation of chromatin organization positive regulation of attachment of mitotic spindle microtubules to kinetochore protein localization to spindle microtubule RNA localization to chromatin cellular response to leukemia inhibitory factor adaptive thermogenesis positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity positive regulation of stem cell proliferation negative regulation of stem cell differentiation positive regulation of cytoplasmic translation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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