Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 13 publications 13 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Published species |
Human, Mouse, Pig, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
HO-1/HMOX1 Fusion Protein Ag26172 (151-288 aa encoded by BC001491) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.2 mg/mL |
Storage conditions |
-20°C |
Immunogen sequence: AQKALDLPS SGEGLAFFTF PNIASATKFK QLYRSRMNSL EMTPAVRQRV IEEAKTAFLL NIQLFEELQE LLTHDTKDQS PSRAPGLRQR ASNKVQDSAP VETPRGKPPL NTRSQAPLLR WVLTLSFLVA TVAVGLYAM (151-288 aa encoded by BC001491)
Heme oxygenase (HO) is a microsomal enzyme that catalyzes the oxidation of heme to the antioxidant molecules, biliverdin and carbon monoxide. HO consists of two homologous isozymes, an inducible HO-1 and a constitutively expressed HO-2. HO-1 is induced by a wide variety of stimuli including conditions of oxidative stress, inflammatory agents, transforming growth factor beta and heat shock. The increase in expression of HO-1 is thought to be a cellular defense mechanism against oxidative stress since elevated HO could eventually generate more bilirubin, an anti-oxidant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: heat shock protein, 32-kD; heme orygenase 1; heme oxygenase (decycling) 1; Heme oxygenase 1; Heme oxygenase 1 soluble form; hemoxygenase; HO-1; P32 protein
Gene Aliases: HMOX1; HO; HO1
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