Invitrogen

HOMER1 Polyclonal Antibody

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HOMER1 Antibody in Western Blot (WB) — Western blot analysis of HOMER1 in human/mouse brain. Samples were incubated with polyclonal antibody (Product # PA5-115374).

HOMER1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry analysis of HOMER1 in human lymph cancer tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115374) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.

HOMER1 Antibody in Immunocytochemistry (ICC) — Immunocytochemistry analysis of HOMER1 in HepG2. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115374) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with Alexa Fluor 594 conjugated goat anti-rabbit IgG using a dilution of 1:600.

Product Details

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

Immunohistochemistry (PFA fixed) (IHC (PFA))

1:50-1:200

Immunocytochemistry (ICC)

1:100-1:500

Immunofluorescence (IF)

1:100-1:500

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human HOMER1, corresponding to a region within the internal amino acids.

Conjugate

Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 50% glycerol, 150mM NaCl

Contains

0.02% sodium azide

Storage conditions

-20°C

Target Information

HOMER1 is a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: homer homolog 1; Homer protein homolog 1; homer, neuronal immediate early gene, 1; Homer-1; immediate early gene protein Homer1A; PSD-Zip45; scaffold protein; VASP/Ena-related gene up-regulated during seizure and LTP 1; Vesl-1

Gene Aliases: HOMER; homer-1; HOMER1; HOMER1A; HOMER1B; HOMER1C; HOMER1F; PSD-Zip45; SYN47; Ves-1; Vesl; Vesl-1; Vesl1

UniProt ID: (Human) Q86YM7, (Mouse) Q9Z2Y3, (Rat) Q9Z214

Entrez Gene ID: (Human) 9456, (Mouse) 26556, (Rat) 29546

Molecular Function: signaling molecule

Function(s)

skeletal muscle contraction phospholipase C-activating G-protein coupled glutamate receptor signaling pathway chemical synaptic transmission positive regulation of signal transduction behavioral response to cocaine skeletal muscle fiber development chemical homeostasis within a tissue response to calcium ion positive regulation of calcium ion transport regulation of calcium ion import regulation of store-operated calcium entry regulation of cation channel activity G-protein coupled glutamate receptor signaling pathway protein localization to synapse circadian rhythm response to nicotine response to cocaine

Process(es)

protein binding G-protein coupled glutamate receptor binding signaling adaptor activity ion channel binding receptor binding type 5 metabotropic glutamate receptor binding protein complex scaffold identical protein binding protein heterodimerization activity scaffold protein binding

HOMER1 Polyclonal Antibody

Product Details

Target Information

References (0)

Bioinformatics

Material safety data sheets (MSDS)

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