In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation.
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Protein Aliases: homeo box 1E; homeo box A3; Homeobox protein Hox-1E; Homeobox protein Hox-A3; Hox-1.5-like protein; Hox-15
Gene Aliases: HOX1; HOX1E; HOXA3
UniProt ID: (Human) O43365
Entrez Gene ID: (Human) 3200