OriGene

HOXC11 Monoclonal Antibody (OTI3E10), TrueMAB™

View all (25) HOXC11 antibodies

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Datasheet

Protocols

Questions & Answers

Tech Support

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HOXC11 Antibody in Immunocytochemistry (ICC/IF) — Anti-HOXC11 mouse monoclonal antibody (TA502572) Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HOXC11(RC201475).

HOXC11 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical staining of paraffin-embedded human endometrium tissue within the normal limits using anti-HOXC11 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100°C for 10min, TA502572)

HOXC11 Antibody in Western Blot (WB) — HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HOXC11 (RC201475, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-HOXC1. Positive lysates LY415427 (100 µg) and LC415427 (20 µg) can be purchased separately from OriGene.

HOXC11 Antibody in Flow Cytometry (Flow) — HEK293T cells transfected with either RC201475 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-HOXC11 antibody (TA502572), and then analyzed by flow cytometry.

Product Details

CF502572

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:150	-
Immunocytochemistry (ICC/IF)	1:100	-
Flow Cytometry (Flow)	1:100	-

Product Specifications
Species Reactivity	Human
Host/Isotype	Mouse / IgG1
Class	Monoclonal
Type	Antibody
Clone	OTI3E10
Immunogen	Human recombinant protein fragment corresponding to amino acids 1-304 of human HOXC11 produced in E.coli. View immunogen
Conjugate	Unconjugated
Form	lyophilized
Concentration	1 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.3, with 8% trehalose
Contains	no preservative
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)

Target Information

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene binds to a promoter element of the lactase-phlorizin hydrolase. It also may play a role in early intestinal development. An alternatively spliced variant encoding a shorter isoform has been described but its full-length nature has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: homeo box C11; Homeobox protein Hox-3H; Homeobox protein Hox-C11; MGC4906

Gene Aliases: HOX3H; HOXC11

UniProt ID: (Human) O43248

Entrez Gene ID: (Human) 3227

Molecular Function: homeodomain transcription factor

Function(s)

metanephros development organ induction transcription from RNA polymerase II promoter endoderm development anterior/posterior pattern specification proximal/distal pattern formation embryonic digit morphogenesis positive regulation of transcription from RNA polymerase II promoter embryonic skeletal joint morphogenesis

Process(es)

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding

HOXC11 Monoclonal Antibody (OTI3E10), TrueMAB™

Product Details

CF502572

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Species Reactivity

Host/Isotype

Class

Type

Clone

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

References (0)

Bioinformatics

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