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The protein is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HGPRT; HGPRTase; HPRT 1; Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 1; testicular tissue protein Li 89
Gene Aliases: HGPRT; HPRT; HPRT1
UniProt ID: (Human) P00492
Entrez Gene ID: (Human) 3251
Molecular Function:
glycosyltransferase
isomerase
mutase
transferase
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