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Product Details
MA5-15381
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
ELISA (ELISA) |
1:10,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Mouse / IgG2a |
Class |
Monoclonal |
Type |
Antibody |
Clone |
5G12G2 |
Immunogen |
Purified recombinant fragment of HPS1 expressed in E. Coli. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
Conc. Not Determined |
Storage buffer |
ascites |
Contains |
0.03% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_10985320 |
Product Specific Information
MA5-15381 targets HPS1 in WB applications and shows reactivity with Human samples.
The MA5-15381 immunogen is purified recombinant fragment of HPS1 expressed in E. Coli.
.
Target Information
Hermansky-Pudlak syndrome (HPS) is a rare, genetically heterogeneous, autosomal recessive disorder. It is characterized by oculocutaneous albinism, lysosomal storage defects and prolonged bleeding due to platelet storage pool deficiency. There are 10 HPS genes encoding HPS proteins that all interact within three distinct ubiquitously expressed protein complexes or biogenesis of lysosome-related organelle complexes. Defects in these genes cause HPS. HSP-1 is a component of multiple cytoplasmic organelles and is important for their normal development and function. It plays a role in intracellular protein sorting.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BLOC-3 complex member HPS1; Hermansky-Pudlak syndrome 1 protein; MGC5277
Gene Aliases: BLOC3S1; HPS; HPS1
UniProt ID: (Human) Q92902
Entrez Gene ID: (Human) 3257
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