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|Tested species reactivity||Human|
|Published species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (CTSYNMDRFINK) corresponding to the C-terminus amino acids of HSD11B1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.3-2 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
This antibody is predicted to react with bovine based on sequence homology.
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes.
PA5-18331 was used in western blot to investigate hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter in db/db mice as
|Wang Y,Nakagawa Y,Liu L,Wang W,Ren X,Anghel A,Lutfy K,Friedman TC,Liu Y||Diabetologia (54:440)||2011|
11-beta-HSD1; 11-DH; corticosteroid 11-beta-dehydrogenase isozyme 1; HDL; HSD11; HSD11B; HSD11B1; HSD11L; hydroxysteroid (11-beta) dehydrogenase 1; MGC13539; OTTHUMP00000034650; SDR26C1; short chain dehydrogenase/reductase family 26C member 1; short chain dehydrogenase/reductase family 26C, member 1
11-beta-HSD1; 11-DH; CORTRD2; HDL; HSD11; HSD11B; HSD11B1; HSD11L; SDR26C1