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|Tested species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 90 and 300 of Human HSP47|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
PA5-27832 targets HSP47 in WB and IHC (P) applications and shows reactivity with Human and mouse samples.
The PA5-27832 immunogen is recombinant fragment corresponding to a region within amino acids 90 and 300 of Human HSP47.
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. The protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to this protein have been found in patients with rheumatoid arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Activation of ¿7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-¿ Production.
PA5-27832 was used in immunohistochemistry - paraffin section to elucidate the mechanism of alpha7nAChr in promoting diabetic wound healing by supression of TNF-alpha-production
|Dong MW,Li M,Chen J,Fu TT,Lin KZ,Ye GH,Han JG,Feng XP,Li XB,Yu LS,Fan YY||Inflammation (39:687)||2016|
47 kDa heat shock protein; Arsenic-transactivated protein 3; AsTP3; beta enolase repressor factor 1; CBP1; CBP2; Cell proliferation-inducing gene 14 protein; clade H (; collagen binding protein 1; Collagen-binding protein; Colligin; colligin-1; colligin-2; gp46; HSP47; OI10; PPROM; RA-A47; rheumatoid arthritis antigen A-47; Rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) proteinase inhibitor; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2); Serine protease inhibitor J6; Serpin H1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); SERPINH2
AsTP3; BERF-1; CBP1; CBP2; gp46; HSP47; J6; OI10; PIG14; PPROM; RA-A47; SERPINH1; SERPINH2