Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases.
Frontiers in pharmacology
Suárez-Rivero JM,Pastor-Maldonado CJ,Romero-González A,Gómez-Fernandez D,Povea-Cabello S,Álvarez-Córdoba M,Villalón-García I,Talaverón-Rey M,Suárez-Carrillo A,Munuera-Cabeza M,Sánchez-Alcázar JA
MA3-012 was used in Western Blotting to identify a potentially beneficial molecule, pterostilbene (a resveratrol analogue), as mitochondrial booster in drug screenings.
Tue Apr 05 00:00:00 EDT 2022
Proteomic Analysis of m.8296A>G Variation in the Mitochondrial tRNA Lys Gene.
Maraş Genç H,Akpınar G,Kasap M,Uyur Yalçın E,Üstek D,Aslanger AD,Kara B
MA3-012 was used in Western Blotting to study the mitochondrial proteome in a patient with m.8296A>G variation to elucidate the effects of this mutation at the protein level.
Fri Jul 01 00:00:00 EDT 2022
UPRmt activation improves pathological alterations in cellular models of mitochondrial diseases.
Orphanet journal of rare diseases
Suárez-Rivero JM,Pastor-Maldonado CJ,Povea-Cabello S,Álvarez-Córdoba M,Villalón-García I,Talaverón-Rey M,Suárez-Carrillo A,Munuera-Cabeza M,Reche-López D,Cilleros-Holgado P,Piñero-Perez R,Sánchez-Alcázar JA
MA3-012 was used in Western Blotting to provide compelling evidence to propose the activation of intrinsic cellular compensatory mechanisms as promising therapeutic strategy for mitochondrial diseases.
Tue May 17 00:00:00 EDT 2022
The Role of Nonglycolytic Glucose Metabolism in Myocardial Recovery Upon Mechanical Unloading and Circulatory Support in Chronic Heart Failure.
Badolia R,Ramadurai DKA,Abel ED,Ferrin P,Taleb I,Shankar TS,Krokidi AT,Navankasattusas S,McKellar SH,Yin M,Kfoury AG,Wever-Pinzon O,Fang JC,Selzman CH,Chaudhuri D,Rutter J,Drakos SG
MA3-012 was used in Western Blotting to provide further insights into mechanisms responsible for the beneficial effect of glycolysis induction during the recovery of failing human hearts after mechanical unloading.
Tue Jul 21 00:00:00 EDT 2020
A Study into the ADP-Ribosylome of IFN-γ-Stimulated THP-1 Human Macrophage-like Cells Identifies ARTD8/PARP14 and ARTD9/PARP9 ADP-Ribosylation.
Journal of proteome research
Higashi H,Maejima T,Lee LH,Yamazaki Y,Hottiger MO,Singh SA,Aikawa M
MA3-012 was used in Western Blotting to identify interferon-γ-induced ADP-ribosylation substrates in macrophages.
Fri Apr 05 00:00:00 EDT 2019
Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms.
Solis GM,Kardakaris R,Valentine ER,Bar-Peled L,Chen AL,Blewett MM,McCormick MA,Williamson JR,Kennedy B,Cravatt BF,Petrascheck M
MA3-012 was used in Western Blotting to examine the beneficial effects of tetracyclines in models of neurodegenerative disease.
Tue Nov 27 00:00:00 EST 2018
Multiplexed 3D super-resolution imaging of whole cells using spinning disk confocal microscopy and DNA-PAINT.
Schueder F,Lara-Gutiérrez J,Beliveau BJ,Saka SK,Sasaki HM,Woehrstein JB,Strauss MT,Grabmayr H,Yin P,Jungmann R
MA3-012 was used in Immunocytochemistry to combine 3D DNA points accumulation for imaging in nanoscale topography with spinning disk confocal hardware to remove the requirement of complex hardware for single-molecule localisation microscopy in thick samples.
Tue Dec 12 00:00:00 EST 2017
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function.
Zhang T,Du W,Wilson AF,Namekawa SH,Andreassen PR,Meetei AR,Pang Q
MA3012 was used in western blot to explore the role of Fancd2 in normal development and tumorigenesis
Wed Apr 05 00:00:00 EDT 2017
CCN6 regulates mitochondrial function.
Journal of cell science
Patra M,Mahata SK,Padhan DK,Sen M
MA3-012 was used in western blot to determine regulation of mitochondrial function via a Wnt induced signaling protein-3 called CCN6
Fri Jul 15 00:00:00 EDT 2016
Adipocytes from New Zealand obese mice exhibit aberrant proinflammatory reactivity to the stress signal heat shock protein 60.
Journal of diabetes research
Märker T,Kriebel J,Wohlrab U,Burkart V,Habich C
MA3-012 was used in Binding experiments to study whether adipocytes of diabetes-predisposed mice exhibit an increased proinflammatory reactivity to Hsp60.
Tue Oct 28 00:00:00 EDT 2014
Synergistic and differential modulation of immune responses by Hsp60 and lipopolysaccharide.
The Journal of biological chemistry
Osterloh A,Kalinke U,Weiss S,Fleischer B,Breloer M
MA3-012 was used in blocking/activating experiment to investigate the HSP60-mediated immune responses and its relation with lipopolysaccharide
Fri Feb 16 00:00:00 EST 2007
Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase.
The Journal of biological chemistry
Ahuja N,Schwer B,Carobbio S,Waltregny D,North BJ,Castronovo V,Maechler P,Verdin E
MA3-012 was used in western blot to study the regulation of insulin secretion by SIRT4
Fri Nov 16 00:00:00 EST 2007
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase.
The Journal of cell biology
Schwer B,North BJ,Frye RA,Ott M,Verdin E
MA3-012 was used in western blot to characterize a new mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase .
Mon Aug 19 00:00:00 EDT 2002
The identification of secreted heat shock 60 -like protein from rat glial cells and a human neuroblastoma cell line.
Bassan M,Zamostiano R,Giladi E,Davidson A,Wollman Y,Pitman J,Hauser J,Brenneman DE,Gozes I
MA3-012 was used in western blot to study the effect of vasoactive intestinal peptide and temperature on hsp60 expression in glial and neuroblastoma cells
Fri Jun 26 00:00:00 EDT 1998
Simultaneous overexpression of two stress proteins in rat cardiomyocytes and myogenic cells confers protection against ischemia-induced injury.
Lau S,Patnaik N,Sayen MR,Mestril R
MA3-012 was used in immunocytochemistry to investigate the protective effect of HSP60 and HSP10 on myogenic cells against ischemia/reperfusion injury
Tue Oct 07 00:00:00 EDT 1997
Immunoelectron microscopic localization of the 60-kDa heat shock chaperonin protein (Hsp60) in mammalian cells.
Experimental cell research
Soltys BJ,Gupta RS
MA3-012 was used in immunohistochemistry to investigate the localization of the 60-kDa heat shock chaperonin protein
Wed Jan 10 00:00:00 EST 1996
Chaperonin-mediated protein folding: GroES binds to one end of the GroEL cylinder, which accommodates the protein substrate within its central cavity.
The EMBO journal
Langer T,Pfeifer G,Martin J,Baumeister W,Hartl FU
MA3-012 was used in western blot to investigate the important role of GroEL in protein folding
Tue Dec 01 00:00:00 EST 1992