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Product Details
CL488-66723
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3H5A5
Immunogen
Recombinant Protein
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
2 mg/mL
Purification
Protein G
Storage buffer
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Target Information
HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. This protein inhibits HSPA8/HSC70 ATPase and chaperone activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Antigen NY-CO-25; heat shock 105kD alpha; heat shock 105kD beta; heat shock 105kDa/110kDa protein 1; Heat shock 110 kDa protein; Heat shock protein; Heat shock protein 105 kDa; Heat shock protein family H member 1; HSP; NY CO 25
Gene Aliases: HSP105; HSP105A; HSP105B; HSP110; HSPH1; KIAA0201; NY-CO-25
UniProt ID: (Human) Q92598
Entrez Gene ID: (Human) 10808
receptor-mediated endocytosis
response to unfolded protein
positive regulation of MHC class I biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
chaperone mediated protein folding requiring cofactor
positive regulation of NK T cell activation
positive regulation of protein tyrosine kinase activity
regulation of cellular response to heat
negative regulation of establishment of protein localization to mitochondrion
negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
negative regulation of p38MAPK cascade
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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