HYB 170-06-02 is specific for human haptoglobin.
HYB 170-06-02 has been successfully used in ELISA techniques. Used as detection antibody in sandwich ELISA with a coat of polyclonal rabbit anti human haptoglobin and subsequently human plasma, HYB 170-06-02 reacts strongly with haptoglobin.
The HYB 170-06-02 immunogen is human haptoglobin purified from pooled serum.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
Haptoglobin is an a2-globulin plasma protein synthesized in the liver. It is an acute phase protein which aslo acts as a scavenger of hemoglobin from hemolyzed red cells. The haptoglobin monomer consists of two a and two ß chains; the a chanins bay be hp1Fa, hp1Sa, or hp2a types while the ß chain is constant. Three major phenotypes are recognized: HP1-1, Hp2-1 and Hp-2-2, in which the hp1a chain bay be either the F or S type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: binding peptide; Bp; Haptoglobin; Haptoglobin alpha chain; haptoglobin alpha(1S)-beta; haptoglobin alpha(2FS)-beta; Haptoglobin beta chain; haptoglobin, alpha polypeptide; haptoglobin, beta polypeptide; HP; HPT; Zonulin
Gene Aliases: BP; HP; HP2ALPHA2; HPA1S
UniProt ID: (Human) P00738
Entrez Gene ID: (Human) 3240
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule