|Tested species reactivity||Virus|
|Host / Isotype||Mouse / IgG1|
|Immunogen||A highly antigenic polypeptide consisting of atleast 60 residues in length, which were selected from genes encoding the NS-3 region of Chinese HCV strains|
|Storage buffer||PBS, pH 7.0|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-21376 detects HCV NS3.
MA1-21376 has been successfully used in ELISA, Immunohistochemistry and Western blot procedures.
The MA1-21376 immunogen is a synthetic peptide corresponding to residues 1378-1458, encoding the NS-3 region of Chinese HCV strains.
HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non-structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.