|Tested species reactivity||Virus|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide corresponding to the NS-5 antigen region of the native protein.|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunohistochemistry (Frozen) (IHC (F))||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunocytochemistry (ICC)||See 1 publications below|
In Western blot, this antibody detects a major band of ~50 kDa with minor bands at ~35, ~40, and ~67 kDa. This reflects bands found in DTT reduced blots fo the immunizing antigen and in immunoblots using a known antibody-positive serum.
The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A.
MA1-82923 was used in immunocytochemistry to assess the interference of HCV replication through the autolysosomal degradation of NS5A by the interferon-inducible protein SCOTIN
|Kim N,Kim MJ,Sung PS,Bae YC,Shin EC,Yoo JY||Nature communications (7:null)||2016|