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Leinco Technologies
Hepsin Monoclonal Antibody (3H10.1), Functional Grade, In Vivo PLATINUM™
Product Details
H5505-1MG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
3H10.1
Immunogen
Human hepsin protein
Conjugate
Form
Liquid
Concentration
≥5.0 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.2-7.4
Contains
no preservative
Storage conditions
4°C short term, -80°C long term
Shipping conditions
Wet ice
Product Specific Information
Specificity: Clone 3H10.1.2 is able to recognize full-length native Hepsin expressed on the cell surface in addition to the recombinant soluble form.
Endotoxin Level: <0.5 EU/mg as determined by the LAL method.
Purity: ≥98% monomer by analytical SEC and >95% by SDS Page.
Preparation: Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Pathogen Testing: To protect mouse colonies from infection by pathogens and to assure that experimental preclinical data is not affected by such pathogens, all of Leinco Purified Functional PLATINUM™ antibodies are tested and guaranteed to be negative for all pathogens in the IDEXX IMPACT I Mouse Profile.
Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80C. Avoid Repeated Freeze Thaw Cycles.
Target Information
Hepsin is a cell surface serine protease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Serine protease hepsin; testicular tissue protein Li 85; Transmembrane protease serine 1
Gene Aliases: HPN; TMPRSS1
UniProt ID: (Human) P05981
Entrez Gene ID: (Human) 3249
proteolysis
regulation of cell shape
positive regulation of gene expression
negative regulation of epithelial to mesenchymal transition
positive regulation of plasminogen activation
positive regulation of cell growth
basement membrane disassembly
negative regulation of apoptotic process
positive regulation by host of viral transcription
hepatocyte growth factor receptor signaling pathway
negative regulation of epithelial cell proliferation
detection of mechanical stimulus involved in sensory perception of sound
potassium ion transmembrane transport
cochlea morphogenesis
response to thyroid hormone
pilomotor reflex
positive regulation of hepatocyte proliferation
positive regulation of thyroid hormone generation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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