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|Tested species reactivity||Human, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A highly antigenic synthetic peptide from the EGF-like domain of human heregulin|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||Assay Dependent|
|Western Blot (WB)||5-10 µg/mL|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-16626 targets Heregulin in IHC and WB applications and shows reactivity with Human and mouse samples.
The PA5-16626 immunogen is a highly antigenic synthetic peptide from the EGF-like domain of human heregulin.
Heregulin (HRG) or neu differentiation factor (NDF) binds to c-erbB-3 and c-erbB-4 receptors on mammary and neuronal cells with low and high affinities, respectively. HRG/NDF exists in several isoforms, which are classified in two groups, alpha and beta that differ in their EGF-like domain and in receptor binding affinity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
acetylcholine receptor-inducing activity; alpha (45kD; ERBB2 p185-activator); glial growth factor; glial growth factor 2; heregulin; heregulin, alpha (45kD, ERBB2 p185-activator); membrane-bound isoform; neu differentiation factor; pro-neuregulin-1; pro-neuregulin-1, membrane-bound isoform; pro-NRG1; sensory and motor neuron derived factor; type I neuregulin 1; type III neuregulin 1
6030402G23Rik; ARIA; D230005F13Rik; GGF; GGF2; GGFII; HGL; HRG; HRG1; HRGA; HRGalpha; MST131; MSTP131; NDF; NRG1; NRG1-IT2; SMDF