|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide, KLH conjugated, corresponding to the C-terminal domain of human Histamine H4 Receptor.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.7|
|Contains||0.01% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-24553 detects Histamine H4 Receptor in human samples.
PA1-24553 has been successfully used in Immunocytochemistry procedures.
The PA1-24553 immunogen corresponds to a synthetic peptide, KLH conjugated, corresponding to the C-terminal domain of human Histamine H4 Receptor. Sequence identity/similarity to Mouse: 58/76%, Rat: 35/41%.
Histamine Receptor H4 binds histamine and several psychoactive compounds such as amitriptyline, chlorpromazine, cyproheptadine, and mianserin. The Histamine H4 receptor has been reported in human blood peripheral leukocytes, bone marrow, colon, liver, lung, smalll intestine, spleen, testis, thymus, tonsil, and trachea. Contrary to the mouse H4 receptor, the human gene was not detected in brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.