Active Motif
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Dot blot (DB) |
Assay-dependent | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
This antibody was raised against a peptide containing human histone H2AQ104me1. |
Conjugate |
Unconjugated |
Form |
Liquid |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.5, with 30% glycerol |
Contains |
0.035% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2793698 |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: H2A histone family, member R; H2A histone family, member X; H2A histone family, member Z; H2A-clustered histone 1; H2a/x; H2A/z; H2AX histone; H2AZ histone; H2B histone family, member U, (testis-specific); histone 1, H2aa; histone 1, H2ba; Histone H2A type 1-A; Histone H2A.X; Histone H2A.Z; Histone H2A/r; Histone H2AX; Histone H2B type 1-A; Histone H2B, testis; Testis-specific histone H2B; TSH2B.1
Gene Aliases: bA317E16.2; bA317E16.3; H2A.X; H2A.z; H2A.Z-1; H2A/X; H2A/z; H2AA; H2AC1; H2AFR; H2AFX; H2AFZ; H2AX; H2AZ; H2AZ1; H2BC1; H2BFU; HIST1H2AA; HIST1H2BA; STBP; TH2A; TH2B; TSH2B; TSH2B.1
UniProt ID: (Human) P16104, (Human) P0C0S5, (Human) Q96QV6, (Human) Q96A08
Entrez Gene ID: (Human) 3014, (Human) 3015, (Human) 221613, (Human) 255626
Molecular Function:
histone
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