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Homer3 Antibody (APZ-028-25UL) in IHC (F)
Expression of Homer3 in rat nucleus basalis - Immunohistochemical staining of perfusion-fixed frozen rat brain sections with Anti-Homer3 Antibody (#APZ-028), (1:1000), followed by goat Anti-rabbit-AlexaFluor-488. Homer3 immunoreactivity (green) appears in cells of the horizontal diagonal band (HDB), (arrows). Cell nuclei are stained with DAPI (blue).
Product Details
APZ-028-25UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)RSQSADAPGPTERER, corresponding to amino acid residues 155-169 of rat Homer3, Intracellular
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homer homolog 3; Homer protein homolog 3; Homer, neuronal immediate early gene, 3; Homer-3; VASP/Ena-related gene up-regulated during seizure and LTP 3; Vesl-3
Gene Aliases: AW146114; HOMER-3; HOMER3; Vesl-3; VESL3
UniProt ID: (Human) Q9NSC5, (Mouse) Q99JP6, (Rat) Q9Z2X5
Entrez Gene ID: (Human) 9454, (Mouse) 26558, (Rat) 29548
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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