|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:1000|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human|
|Published species reactivity||Bacteria|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 381-412 amino acids from the C-terminal region of human HtrA1|
|Purification||Size-exclusion - Dialysis, Ammonium sulfate precipitation|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with rat based on sequence homology.
HtrA1 is a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: High-temperature requirement A serine peptidase 1; IGFBP5-protease; L56; protease, serine, 11 (IGF binding); Serine protease 11; Serine protease HTRA1
Gene Aliases: ARMD7; CADASIL2; CARASIL; HTRA; HTRA1; L56; ORF480; PRSS11
UniProt ID: (Human) Q92743
Entrez Gene ID: (Human) 5654
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