Invitrogen
Catalog # RP-38962
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Control (Ctrl) | Assay Dependent |
Species reactivity | Human |
Host / Isotype | E.coli |
Class | Recombinant |
Type | Protein |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.1 mg/ml |
Purification | purified |
Storage buffer | 0.05M tris HCl, pH 7.5, with 10mM L-glutathione |
Contains | no preservative |
Storage conditions | -20°C or -80°C if preferred |
This product is a GST-tagged recombinant protein corresponding to human CD2, aa 25-209.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 46kDa.
CD2, also known as E-rosette receptor, T11 and lymphocyte-function antigen-2 (LFA-2) is expressed on T cells, thymocytes, and subset of natural killer cells. Human CD2 functions as the receptor for sheep erythrocytes, lck fyn, p59 , CD3eta human CD58 (LFA-3), and CD15s (Sialyl Lewis X). p56and CD3epsilon are tyrosine-phosphorylated after CD2 stimulation. CD2 plays a role in T cell activation, T- or NK-cell-mediated cytolysis, apoptosis in activated peripheral T cells, and regulation of T cell anergy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD2; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5
Gene Aliases: CD2; LFA-2; SRBC; T11
UniProt ID: (Human) P06729
Entrez Gene ID: (Human) 914
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