|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant protein encoding part of the external domain of human CD54|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:20|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-11433 targets CD54 in IHC (P) applications and shows reactivity with Human samples.
The MA5-11433 immunogen is recombinant protein encoding part of the external domain of human CD54.
ICAM-1 (intercellular adhesion molecule) has 7 potential N-linked glycosylation sites. It is a single chain glycoprotein of Ig supergene family, present on unstimulated endo-thelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Diagnostic value of hepatic intercellular adhesion molecule-1 expression in Egyptian infants with biliary atresia and other forms of neonatal cholestasis.
MA5-11433 was used in immunohistochemistry to investigate the usefulness of ICAM-1 for identification of neonatal cholestasis patients
|Ghoneim EM,Sira MM,Abd Elaziz AM,Khalil FO,Sultan MM,Mahmoud AB||Hepatology research : the official journal of the Japan Society of Hepatology (41:763)||2011|
The application of artificial intelligence to microarray data: identification of a novel gene signature to identify bladder cancer progression.
MA5-11433 was used in immunohistochemistry to evaluate a microarray analysis method for identifying gene signature of bladder cancer
|Catto JW,Abbod MF,Wild PJ,Linkens DA,Pilarsky C,Rehman I,Rosario DJ,Denzinger S,Burger M,Stoehr R,Knuechel R,Hartmann A,Hamdy FC||European urology (57:398)||2010|
ICAM-1 is overexpressed by villous trophoblasts in placentitis.
MA5-11433 was used in immunohistochemistry to investigate the ICAM-1 overexpression in villous trophoblasts in human placentitis
|Juliano PB,Blotta MH,Altemani AM||Placenta (27:750)||2006|
Human endometrial epithelial cells (EEC) constitutively express more intercellular adhesion molecule (ICAM)-1 than endometrial stromal cells (ESC) in culture.
MA5-11433 was used in immunocytochemistry to compare the expression level of mICAM-1 in human endometrial epithelial cells and endometrial stromal cells
|Defrère S,Van Langendonckt A,Moulin P,Befahy P,Gonzalez D,Martinez-Madrid B,Dolmans MM,Donnez J||American journal of reproductive immunology (New York, N.Y. : 1989) (54:5)||2005|