|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
MA5-15621 targets ICAM1 in WB applications and shows reactivity with Human samples.
The MA5-15621 immunogen is purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.
MA5-15621 detects ICAM1 which has a predicted molecular weight of approximately 57.8kDa.
This gene encodes a cell surface glycoprotein which is typically expressed on endothelial cells and cells of the immune system. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by Rhinovirus as a receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
¿-Smooth muscle actin-positive myofibroblasts, in association with epithelial-mesenchymal transition and lymphogenesis, is a critical prognostic parameter in patients with oral tongue squamous cell carcinoma.
MA5-15621 was used in immunohistochemistry - paraffin section to study the role of alpha-smooth muscle actin-positive myofibroblasts in the oral tongue squamous cell carcinoma progression
|Ding L,Zhang Z,Shang D,Cheng J,Yuan H,Wu Y,Song X,Jiang H||Journal of oral pathology and medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology (43:335)||2014|