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|Tested species reactivity||Mouse , Human , Rat|
|Host / Isotype||Hamster / IgG|
|Immunogen||Mouse T cell clone D10.G4.1|
|Storage buffer||PBS, pH 7.2|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
CD278 belongs to the CD28 and CTLA-4 cell-surface receptor family and is highly expressed in activated T-cells. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Ailim, CRP-1, H4, CCLP, CD278, AILIM, CVID1, Ly115
activation-inducible lymphocyte immunomediatory molecule, inducible T-cell costimulator, inducible costimulator, CD28 and CTLA-4-like protein, CD28-related protein 1, inducible T-cell co-stimulator, AILIM, CD278, CVID1