|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human IFN alpha 2b|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
M710 targets IFN alpha in ELISA applications and shows reactivity with Human samples.
The M710 immunogen is recombinant human IFN alpha 2b.
M710 detects IFN alpha which has a predicted molecular weight of approximately 19 kDa.
Leukocyte interferon is produced predominantly by B lymphocytes. Immune interferon (IFN-gamma; MIM 147570) is produced by mitogen- or antigen-stimulated T lymphocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
An international comparability study to determine the sources of uncertainty associated with a non-competitive sandwich fluorescent ELISA.
M710 was used in ELISA to evaluate the consistency of a non-competitive sandwich fluorescent ELISA across different laboratories
|Noble JE,Wang L,Cerasoli E,Knight AE,Porter RA,Gray E,Howe C,Hannes E,Corbisier P,Wang J,Wu L,Altieri I,Patriarca M,Hoffman A,Resch-Genger U,Ebert B,Voigt J,Shigeri Y,Vonsky MS,Konopelko LA,Gaigalas AK,Bailey MJ||Clinical chemistry and laboratory medicine (46:1033)||2008|
Human dendritic cells are activated by dengue virus infection: enhancement by gamma interferon and implications for disease pathogenesis.
M710 was used in ELISA to investigate the effect of dengue virus infection on human dendritic cells
|Libraty DH,Pichyangkul S,Ajariyakhajorn C,Endy TP,Ennis FA||Journal of virology (75:3501)||2001|
Endogenous IFN-alpha production by plasmacytoid dendritic cells exerts an antiviral effect on thymic HIV-1 infection.
M710 was used in immunohistochemistry to investigate the mechanism for the inhibition of HIV infection by plasmacytoid dendritic cells
|Gurney KB,Colantonio AD,Blom B,Spits H,Uittenbogaart CH||Journal of immunology (Baltimore, Md. : 1950) (173:7269)||2004|