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|Tested species reactivity||Human, Rabbit|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||IGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Inhibition Assays (IA)||1.5 µg/mL|
|Immunoprecipitation (IP)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-13812 targets IGF-1 Receptor alpha in IA and IP applications and shows reactivity with Human and Rabbit samples.
The MA5-13812 immunogen is iGF-1R/3T3 mouse fibroblasts transfected with human type I IGF-receptor cDNA.
IGF-1R (Insulin-like Growth Factor-1 Receptor) consists of alpha- and beta-subunits, which are disulfide-linked in a beta-alpha-alpha-beta configuration in the mature receptor. The alpha-subunit is completely extracellular, while the beta-subunit spans the membrane and the intracellular portion has intrinsic tyrosine kinase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD221; IGF-I receptor; insulin-like growth factor I receptor; insulin-like growth factor receptor 1; soluble IGF1R variant 1; soluble IGF1R variant 2
CD221; IGF1R; IGFIR; IGFR; JTK13