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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||Purified recombinant fragment of IGF1R-Beta (Amino Acid: 1101-1367) expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15354 targets IGF1R in IHC and WB applications and shows reactivity with Human samples.
The MA5-15354 immunogen is purified recombinant fragment of IGF1R-Beta (Amino Acid: 1101-1367) expressed in E. Coli.
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CD221; IGF-I receptor; insulin-like growth factor I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2
CD221; IGF1R; IGFIR; IGFR; JTK13