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IGF2BP2 Monoclonal Antibody (4C6)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
H00010644-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
4C6
Immunogen
IGF2BP2 (AAH21290, 1 a.a. approximately 598 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: MNKLYIGNLS PAVTADDLRQ LFGDRKLPLA GQVLLKSGYA FVDYPDQNWA IRAIETLSGK VELHGKIMEV DYSVSKKLRS RKIQIRNIPP HLQWEVLDGL LAQYGTVENV EQVNTDTETA VVNVTYATRE EAKIAMEKLS GHQFENYSFK ISYIPDEEVS SPSPPQRAQR GDHSSREQGH APGGTSQARQ IDFPLRILVP TQFVGAIIGK EGLTIKNITK QTQSRVDIHR KENSGAAEKP VTIHATPEGT SEACRMILEI MQKEADETKL AEEIPLKILA HNGLVGRLIG KEGRNLKKIE HETGTKITIS SLQDLSIYNP ERTITVKGTV EACASAEIEI MKKLREAFEN DMLAVNQQAN LIPGLNLSAL GIFSTGLSVL SPPAGPRGAP PAAPYHPFTT HSGYFSSLYP HHQFGPFPHH HSYPEQEIVN LFIPTQAVGA IIGKKGAHIK QLARFAGASI KIAPAEGPDV SERMVIITGP PEAQFKAQGR IFGKLKEENF FNPKEEVKLE AHIRVPSSTA GRVIGKGGKT VNELQNLTSA EVIVPRDQTP DENEEVIVRI IGHFFASQTA QRKIREIVQQ VKQQEQKYPQ GVASQRSK
Target Information
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family. It recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains several four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin-like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: IGF-II mRNA-binding protein 2; IGF2 mRNA-binding protein 2; IGF2BP2; RNA-binding protein; p62; unnamed protein product; VICKZ family member 2
Gene Aliases: IMP-2; IMP2; VICKZ2
UniProt ID: (Human) Q9Y6M1
Entrez Gene ID: (Human) 10644
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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