In direct ELISAs, approximately 10% cross-reactivity with recombinant human IGFBP-1 and less than 1% cross-reactivity with recombinant mouse (rm) IGFBP-2, rmIGFBP-3, rmIGFBP-5, rmIGFBP-6, and rmIGFBP-7 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AFBP; hIGFBP-1; IBP-1; IBP1; IGF-binding protein 1; IGF-BP25; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1); Insulin-like growth factor-binding protein 1
Gene Aliases: Igfbp-1; Igfbp1
UniProt ID: (Mouse) P47876
Entrez Gene ID: (Mouse) 16006