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Invitrogen
IGSF11 Monoclonal Antibody (OTI2H1)
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Product Details
MA5-26624
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2H1
Immunogen
Human recombinant protein fragment corresponding to amino acids 23-241 of IGSF11 produced in E.coli
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2723280
Target Information
Immunoglobulin superfamily member 11 (IGSF11) is a gene located on chromosome 3q13.3, encoding a transmembrane protein that belongs to the immunoglobulin superfamily. IGSF11 is known for its expression in the brain, where it plays a role in neuron-to-neuron adhesion and synaptic organization. The protein is involved in processes such as synapse formation and stabilization, impacting neural connectivity and signaling pathways. IGSF11 is also expressed in other tissues, including the gastrointestinal tract, where it can contribute to cell adhesion functions. Research has linked IGSF11 to cancer biology, as its expression is altered in various cancers, potentially influencing tumor cell adhesion and metastasis. Its role in modulating cell signaling pathways makes it an interesting target for therapeutic interventions in both neurological disorders and cancer. Current studies are focusing on its functional implications in synaptic plasticity and tumor progression, providing valuable insights into IGSF11's diverse biological roles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brain and testis-specific immunoglobin superfamily protein; Brain and testis-specific immunoglobulin superfamily protein; Bt-IGSF; cancer/testis antigen 119; CXADR like 1; IgSF11; Immunoglobulin superfamily member 11; immunoglobulin superfamily, member 11; V-set and immunoglobulin domain containing 3; V-set and immunoglobulin domain-containing protein 3
Gene Aliases: BT-IgSF; BTIGSF; CT119; CXADRL1; IGSF11; Igsf13; VSIG3
UniProt ID: (Human) Q5DX21
Entrez Gene ID: (Human) 152404
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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