MA5-15377 targets IKBKE in WB applications and shows reactivity with Human samples.
The MA5-15377 immunogen is purified recombinant fragment of IKBKE (aa1-257) expressed in E. Coli.
IKBKE is a noncanonical I-kappa-B kinase that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines .
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Protein Aliases: I-kappa-B kinase epsilon; IKBKE; IKK-E; IKK-epsilon; IKK-i; IKK-related kinase epsilon; Inducible I kappa-B kinase; inducible IkappaB kinase; Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Gene Aliases: IKBKE; IKK-E; IKK-i; IKKE; IKKI; KIAA0151
UniProt ID: (Human) Q14164
Entrez Gene ID: (Human) 9641