Invitrogen

IKK epsilon Monoclonal Antibody (T.546.3)

Product Image Gallery

IKK epsilon Antibody in Western Blot (WB) — Western blot analysis of IKK Epsilon in recombinant GST-IKK-epsilon and lysates from Ramos cells using IKK Epsilon monoclonal antibody (Product # MA5-14817).

Product Details

Tested Applications

Dilution

Immunoprecipitation (IP)

1:100

Western Blot (WB)

1:1000

Product Specifications

Species Reactivity

Human, Non-human primate

Host / Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

T.546.3

Immunogen

Synthetic peptide corresponding to residues surrounding Val345 of human IKK-epsilon

Conjugate

Unconjugated

Form

Liquid

Purification

Affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

<0.02% sodium azide

Storage conditions

-20°C

RRID

AB_10985738

Product Specific Information

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with other IKKs or with TBK1/NAK.

Target Information

IKBKE is a noncanonical I-kappa-B kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: I-kappa-B kinase epsilon; IkBKE; IKK-E; IKK-epsilon; IKK-i; IKK-related kinase epsilon; Inducible I kappa-B kinase; inducible IkappaB kinase; Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Gene Aliases: IKBKE; IKK-E; IKK-i; IKKE; IKKI; KIAA0151

UniProt ID: (Human) Q14164

Entrez Gene ID: (Human) 9641

Molecular Function: kinase non-receptor serine/threonine protein kinase protein kinase transferase