Pro-inflammatory cytokines activate the transcription factor NF-kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF-kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine-
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Protein Aliases: AMCBX1; FIP-3; FIP3; Fip3p; I-kappa-B kinase subunit gamma; IkB kinase subunit gamma; IkB kinase-associated protein 1; IKK-gamma; IKKAP1; IKKG; incontinentia pigmenti; Inhibitor of nuclear factor kappa-B kinase subunit gamma; IP1; IP2; IPD2; NEMO; NF-kappa-B essential modifier; NF-kappa-B essential modulator
Gene Aliases: AMCBX1; FIP-3; FIP3; Fip3p; IKBKG; IKK-gamma; IKKAP1; IKKG; IMD33; IP; IP1; IP2; IPD2; NEMO; ZC2HC9
UniProt ID: (Human) Q9Y6K9
Entrez Gene ID: (Human) 8517