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|Tested species reactivity||Pig|
|Published species reactivity||Pig, Not Applicable|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant swine IL-10.|
|Storage buffer||PBS, pH 7.2|
|Contains||0.1% sodium azide|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-gamma, TNF-alpha, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Heterologous challenge in the presence of maternally-derived antibodies results in vaccine-associated enhanced respiratory disease in weaned piglets.
ASC9109 was used in flow cytometry to study the result of vaccine-associated enhanced respiratory disease in weaned piglets due to heterologous challenge in the presence of maternally-derived antibodies
|Rajao DS,Sandbulte MR,Gauger PC,Kitikoon P,Platt R,Roth JA,Perez DR,Loving CL,Vincent AL||Virology (491:79)||2016|
|Not Applicable||Not Cited||
Characterization of conventional and plasmacytoid dendritic cells in swine secondary lymphoid organs and blood.
ASC9109 was used in flow cytometry to characterize porcine dendritic cells from secondary lymphoid organs
|Jamin A,Gorin S,Le Potier MF,Kuntz-Simon G||Veterinary immunology and immunopathology (114:224)||2006|
Comparison of humoral and cellular immune responses to inactivated swine influenza virus vaccine in weaned pigs.
ASC9109 was used in flow cytometry to compare humoral and cellular immune responses to inactivated swine influenza virus vaccine using pigs.
|Platt R,Vincent AL,Gauger PC,Loving CL,Zanella EL,Lager KM,Kehrli ME,Kimura K,Roth JA||Veterinary immunology and immunopathology (142:252)||2011|
Porcine circovirus type 2 (PCV2) Cap and Rep proteins are involved in the development of cell-mediated immunity upon PCV2 infection.
ASC9109 was used in ELISA to assess the role of the capside, replicase, and Porcine circovirus type 2 in the induction of cell-mediated immunity upon infection
|Fort M,Sibila M,Nofrarías M,Pérez-Martín E,Olvera A,Mateu E,Segalés J||Veterinary immunology and immunopathology (137:226)||2010|
Immune response characteristics following emergency vaccination of pigs against foot-and-mouth disease.
ASC9109 was used in ELISA to study pigs vaccinated with the emergency inactivated foot-and-mouth disease virus vaccine.
|Barnard AL,Arriens A,Cox S,Barnett P,Kristensen B,Summerfield A,McCullough KC||Vaccine (23:1037)||2005|