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|Tested species reactivity||Rat|
|Published species reactivity||Rat|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant rat IL-10.|
|Storage buffer||PBS, pH 7.2|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 3 publications below|
Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-gamma, TNF-alpha, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Trolox mitigates fibrosis in a bile duct ligation model.
ARC9102 was used in western blot to assess the role of trolox in chronic bile duct ligation.
|Galicia-Moreno M,Favari L,Muriel P||Fundamental & clinical pharmacology (27:308)||2013|
|Rat||Not Cited||Antifibrotic and antioxidant effects of N-acetylcysteine in an experimental cholestatic model.||Galicia-Moreno M,Favari L,Muriel P||European journal of gastroenterology & hepatology (24:179)||2012|
|Rat||Not Cited||Adaptor protein Shc acts as an immune-regulator for the LPS-stimulated maturation of bone marrow-derived dendritic cells.||Chen KD,Hsu LW,Goto S,Yeh CW,Nakano T,Lai CY,Chang YC,Hou CH,Wang CC,Cheng YF,Chiu KW,Lin CC,Chen CL||BMC immunology (12:null)||2011|
CSIF; cytokine synthesis inhibitory factor; IL-10; IL10A; interleukin-10; MGC126450; MGC126451; TGIF
Il-10; Il10; IL10X