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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rat / IgG1, kappa|
|Immunogen||Recombinant human Interleukin 10.|
|Storage buffer||PBS, pH 7.2, with BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||5 ul per 1x10^6 cells|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-gamma, TNF-alpha, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
The decidual stromal cells-secreted CCL2 induces and maintains decidual leukocytes into Th2 bias in human early pregnancy.
RHCIL1004 was used in flow cytometry to study the roles of the decidua-derived CCL2 in the Th2 predominance found at the maternal-fetal interface.
|He YY,He XJ,Guo PF,Du MR,Shao J,Li MQ,Li DJ||Clinical immunology (Orlando, Fla.) (145:161)||2012|
IL-10 and IL-10 receptor overexpression in oral giant cell lesions.
RHCIL1004 was used in immunohistochemistry - frozen section to determine the expression of IL-10 and its receptor in central giant cell lesions and peripheral giant cell lesions.
|Syrio NF,Faria DR,Gomez RS,Gollob KJ,Dutra WO,Souza PE||Medicina oral, patologi¿a oral y cirugi¿a bucal (16:e488)||2011|
CSIF; cytokine synthesis inhibitory factor; IL10A; MGC126450; MGC126451; T-cell growth inhibitory factor; TGIF
CSIF; GVHDS; IL-10; IL10; IL10A; TGIF