Note: You clicked on an external link, which has been disabled in order to keep your shopping session open.
|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human IL-12.|
|Storage buffer||PBS, pH 7.5, with 5mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ELISA (ELISA)||See 2 publications below|
This product is recommended as a detection antibody in Sandwich ELISA applications.
This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DC-SIGN, but not sDC-SIGN, can modulate IL-2 production from PMA- and anti-CD3-stimulated primary human CD4 T cells.
||Martinez O,Brackenridge S,El-Idrissi Mel-A,Prabhakar BS||International immunology (17:769)||2005|
Synthetic TLR agonists reveal functional differences between human TLR7 and TLR8.
||Gorden KB,Gorski KS,Gibson SJ,Kedl RM,Kieper WC,Qiu X,Tomai MA,Alkan SS,Vasilakos JP||Journal of immunology (Baltimore, Md. : 1950) (174:1259)||2005|
IL-12B, NKSF, NFSK, IL-12A, CLMF2, NKSF1, CLMF, P35, NKSF2
CLMF p35, IL-12 subunit p35, IL-12, subunit p35, IL35 subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, cytotoxic lymphocyte maturation factor 1, p35, cytotoxic lymphocyte maturation factor 35 kDa subunit, interleukin 12, p35, interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, CLMF p40, IL-12 subunit p40, IL12, subunit p40, NK cell stimulatory factor chain 2, cytotoxic lymphocyte maturation factor 40 kDa subunit, interleukin 12, p40, interleukin-12 beta chain, interleukin-12 subunit beta, natural killer cell stimulatory factor, 40 kD subunit, IL12A/B, IL-12A, IL-12B, IL12AB, Interleukin-12 p70, IL-12 p75, IL12p35, IL12P40