|Tested species reactivity||Mouse, Rat|
|Published species reactivity||Rat, Not Applicable|
|Host / Isotype||Rat / IgG2a|
|Storage buffer||proprietary buffer|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 2 publications below|
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Blocking lymphocyte trafficking with FTY720 prevents inflammation-sensitized hypoxic-ischemic brain injury in newborns.
A14782 was used in flow cytometry to investigate the role of Th17-helper 17-like lymphocytes in lipopolysaccharide-sensitized neonatal hypoxic-ischemic brain injury
|Yang D,Sun YY,Bhaumik SK,Li Y,Baumann JM,Lin X,Zhang Y,Lin SH,Dunn RS,Liu CY,Shie FS,Lee YH,Wills-Karp M,Chougnet CA,Kallapur SG,Lewkowich IP,Lindquist DM,Murali-Krishna K,Kuan CY||The Journal of neuroscience : the official journal of the Society for Neuroscience (34:16467)||2014|
|Not Applicable||Not Cited||
Anti-IL-23 antibody blockade of IL-23/IL-17 pathway attenuates airway obliteration in rat orthotopic tracheal transplantation.
A14782 was used in flow cytometry to characterize attenuation of airway obliteration in rat orthotopic tracheal transplantation by Anti-IL-23 antibody blockade of IL-23/IL-17 pathway
|Cao H,Lan Q,Shi Q,Zhou X,Liu G,Liu J,Tang G,Qiu C,Qiu C,Xu J,Fan H,Liu Z||International immunopharmacology (11:569)||2011|