|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human IL18R transfected into p815 cells.|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Neat-1:10 (10 µl for 10^6 cells in 100 µl)|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 1 publications below|
MA1-20259 detects IL-18R1 in human samples.
MA1-20259 has been successfully used in FACS procedures. Use 10µl of the suggested working dilution to label 10^6 cells or 100µl whole blood.
The MA1-20259 immunogen is human IL18R transfected p815 cells.
Store at 4°C or at -20°C if preferred, avoiding freeze/thaw cycles. Store in the dark.
IL18R1 is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Apheresis-related enrichment of CD26++ T lymphocytes: phenotypic characterization and correlation with unfavorable outcome in autologous hematopoietic progenitor cell transplantation.
MA1-20259 was used in flow cytometry to study apheresis-related enrichment of CD26++ T lymphocytes and poor prognosis of autologous hematopoietic progenitor cell transplants
|Hildebrandt M,Dijkstra D,Gollasch H,Daemen K,Stevanovic-Meyer M,Ludwig WD||Transfusion (52:765)||2012|